Ambronil
Generic Name
Ambroxol Hydrochloride
Manufacturer
ACI Limited
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ambronil 6 mg pediatric drop | ৳ 30.00 | N/A |
Description
Overview of the medicine
Ambroxol is a mucolytic agent used to treat respiratory diseases associated with viscid or excessive mucus. It helps to thin and loosen mucus in the airways, making it easier to cough up.
Uses & Indications
Dosage
Adults
Not applicable for pediatric drop form; refer to adult formulations.
Elderly
Not applicable for pediatric drop form; refer to adult formulations.
Renal_impairment
Dosage adjustment may be required in severe renal impairment. Consult a physician.
How to Take
Administer orally, preferably with food. Use the provided dropper for accurate dosing. Do not exceed the recommended dose.
Mechanism of Action
Ambroxol acts as a secretolytic and secretomotor agent. It increases serous mucus secretion in the respiratory tract, reduces mucus viscosity, and activates the mucociliary escalator, facilitating mucus clearance.
Pharmacokinetics
Onset
Within 30 minutes
Excretion
Mainly via the kidneys, mostly as metabolites.
Half life
Approximately 7-12 hours
Absorption
Rapidly and almost completely absorbed from the gastrointestinal tract.
Metabolism
Primarily in the liver to inactive metabolites.
Side Effects
Contraindications
- •Hypersensitivity to ambroxol or any component of the formulation.
- •Hereditary problems of fructose intolerance (due to sorbitol content in some formulations).
Drug Interactions
Antitussives (cough suppressants)
Concomitant use may lead to a build-up of secretions due to the impaired cough reflex.
Antibiotics (e.g., amoxicillin, cefuroxime, erythromycin, doxycycline)
Ambroxol may increase the penetration of these antibiotics into bronchial secretions.
Storage
Store below 30°C, away from light and moisture. Do not freeze.
Overdose
Symptoms may include nausea, vomiting, diarrhea, and epigastric pain. Management is primarily supportive and symptomatic. Gastric lavage and induced emesis are generally not required.
Pregnancy & Lactation
Ambroxol crosses the placental barrier. While studies show no direct harmful effects on pregnancy, it's generally not recommended during the first trimester. Use in later trimesters and during lactation only if clearly necessary and under medical supervision. Ambroxol is excreted in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date (unopened).
Availability
Pharmacies, hospitals
Approval Status
Approved in Bangladesh (DGDA)
Patent Status
Generic available
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Global Brand Names
International brand names for this medicine
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