Apidone
Generic Name
Apidone
Manufacturer
MediCorp Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| apidone 5 mg suspension | ৳ 38.00 | N/A |
Description
Overview of the medicine
Apidone 5 mg Suspension is an antihistamine medication primarily used to relieve symptoms of allergies such as sneezing, runny nose, watery eyes, and itching. It works by blocking histamine, a natural substance that the body produces during an allergic reaction.
Uses & Indications
Dosage
Adults
5 mg (10 mL) once daily.
Elderly
No dosage adjustment is generally required for elderly patients with normal renal function.
Renal_impairment
For patients with moderate to severe renal impairment (creatinine clearance <50 mL/min), the dose should be reduced to 5 mg (10 mL) every other day or as directed by physician.
How to Take
Apidone suspension is for oral administration only. It can be taken with or without food. Shake the bottle well before each use. Use the provided measuring spoon or cup for accurate dosing.
Mechanism of Action
Apidone acts as a selective peripheral H1-receptor antagonist. It competitively binds to and blocks peripheral histamine H1 receptors, thereby preventing the actions of histamine, such as vasodilation, increased vascular permeability, itching, and bronchoconstriction. This results in the reduction of allergic symptoms.
Pharmacokinetics
Onset
Within 30 minutes to 1 hour.
Excretion
Mainly excreted unchanged via urine and feces.
Half life
Approximately 12-15 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract following oral administration. Peak plasma concentrations are typically reached within 1-2 hours.
Metabolism
Undergoes minimal hepatic metabolism, primarily excreted unchanged.
Side Effects
Contraindications
- •Hypersensitivity to Apidone or any component of the formulation.
- •Patients with severe renal impairment (end-stage renal disease).
Drug Interactions
Ketoconazole, Erythromycin
May slightly increase Apidone plasma levels, though generally not clinically significant.
Central Nervous System Depressants
Concurrent use with alcohol, benzodiazepines, or other CNS depressants may enhance drowsiness.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children. Do not freeze.
Overdose
Symptoms of overdose may include drowsiness, tachycardia, headache, and dizziness. In case of overdose, symptomatic and supportive treatment should be initiated. There is no specific antidote.
Pregnancy & Lactation
Pregnancy Category B. Apidone should be used during pregnancy only if clearly needed. It is unknown whether Apidone is excreted in human milk; therefore, caution should be exercised when Apidone is administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from the manufacturing date, consult packaging for exact expiry.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Generic available
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Global Brand Names
International brand names for this medicine
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