Apnac
Generic Name
Nifedipine
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| apnac 50 mg tablet | ৳ 0.80 | N/A |
Description
Overview of the medicine
Apnac (Nifedipine) is a calcium channel blocker used to treat hypertension and angina.
Uses & Indications
Dosage
Adults
20 mg three times daily, may be increased gradually up to 120 mg/day.
Elderly
Lower initial dose of 10 mg three times daily, titrate slowly.
Renal_impairment
Use with caution, no specific dosage adjustment needed.
How to Take
Administer orally, with or without food.
Mechanism of Action
Nifedipine inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle, resulting in vasodilation and reduced myocardial contractility.
Pharmacokinetics
Onset
30-60 minutes
Excretion
Renal excretion as inactive metabolites
Half life
2-5 hours
Absorption
Rapidly absorbed after oral administration.
Metabolism
Hepatic via CYP3A4
Side Effects
Contraindications
- •Hypersensitivity to Nifedipine
- •Cardiogenic Shock
- •Advanced Aortic Stenosis
Drug Interactions
Beta-Blockers
May cause hypotension and heart failure.
CYP3A4 Inhibitors
May increase Nifedipine levels.
Storage
Store below 30°C, protected from light and moisture.
Overdose
Symptoms include hypotension, bradycardia, and cardiac arrest. Treatment is supportive and symptomatic, including IV fluids, vasopressors, and calcium gluconate.
Pregnancy & Lactation
Category C: Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Exercise caution when administering to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies and Hospitals
Approval Status
DGDA Approved
Patent Status
Off-Patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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