Aristomox
Generic Name
Amoxicillin
Manufacturer
Aristopharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| aristomox 125 mg suspension | ৳ 70.00 | N/A |
Description
Overview of the medicine
Aristomox 125 mg Suspension is an antibiotic medication containing Amoxicillin, belonging to the penicillin group. It is used to treat a wide range of bacterial infections.
Uses & Indications
Dosage
Adults
This strength (125 mg) is primarily for pediatric use. For adult infections, higher strengths are typically prescribed. Consult a physician for appropriate dosing.
Elderly
No specific dose adjustment for elderly with normal renal function. Dose reduction may be necessary in case of severe renal impairment.
Renal_impairment
Dosage adjustment is necessary for patients with impaired renal function. Consult physician for guidance based on creatinine clearance.
How to Take
Administer orally, usually every 8 hours (three times daily) or as directed by the physician. Shake the suspension bottle well before each use. Can be taken with or without food.
Mechanism of Action
Amoxicillin works by inhibiting the synthesis of bacterial cell walls, leading to bacterial cell lysis and death. It is bactericidal.
Pharmacokinetics
Onset
Within 1-2 hours.
Excretion
Primarily excreted unchanged by the kidneys (glomerular filtration and tubular secretion).
Half life
Approximately 1 to 1.5 hours in adults with normal renal function.
Absorption
Rapid and well absorbed from the gastrointestinal tract. Food has minimal effect on absorption.
Metabolism
Partially metabolized in the liver to inactive metabolites (e.g., penicilloic acid).
Side Effects
Contraindications
- •Known hypersensitivity to penicillin antibiotics or any component of the formulation.
- •History of severe allergic reaction (e.g., anaphylaxis) to any beta-lactam antibiotic.
- •Infectious mononucleosis (may cause rash).
Drug Interactions
Probenecid
Increases and prolongs amoxicillin blood levels by decreasing renal tubular secretion.
Allopurinol
Increased incidence of skin rash, especially in patients with hyperuricemia.
Oral Contraceptives
May reduce the efficacy of oral contraceptives.
Warfarin and other oral anticoagulants
May prolong prothrombin time; monitor INR.
Storage
Store dry powder below 30°C, protected from light and moisture. Once reconstituted, store in a refrigerator (2-8°C) and do not freeze.
Overdose
Symptoms of overdose may include gastrointestinal disturbances (nausea, vomiting, diarrhea), fluid and electrolyte imbalance, and crystalluria (renal failure in severe cases). Treatment is supportive and symptomatic; hemodialysis may be used to remove amoxicillin from circulation.
Pregnancy & Lactation
Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus, but there are no adequate and well-controlled studies in pregnant women. Use only if clearly needed. Amoxicillin is excreted in breast milk; use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Dry powder: 2-3 years (refer to package for exact date). Reconstituted suspension: 7-14 days when stored in a refrigerator (as per manufacturer's instructions).
Availability
Available in pharmacies and hospitals
Approval Status
Approved by FDA/DGDA
Patent Status
Generic (Off-patent)
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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