Azimon
Generic Name
Azithromycin 200 mg/5 ml Suspension
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| azimon 200 mg suspension | ৳ 90.00 | N/A |
Description
Overview of the medicine
Azimon 200 mg suspension is an antibiotic belonging to the macrolide group, used to treat various bacterial infections including respiratory tract infections, skin and soft tissue infections, and sexually transmitted diseases.
Uses & Indications
Dosage
Adults
Typically, 500 mg (12.5 ml of 200 mg/5 ml suspension) as a single dose for certain STIs, or 500 mg once daily for 3 days (12.5 ml daily).
Elderly
Dosage adjustment not generally required for elderly patients with normal renal and hepatic function.
Children
10 mg/kg orally once daily for 3 days, or 10 mg/kg on day 1 followed by 5 mg/kg on days 2-5. Maximum dose 500 mg/day.
Renal_impairment
No dosage adjustment required for mild to moderate renal impairment. Use with caution in severe renal impairment (CrCl < 10 mL/min).
How to Take
Shake well before use. Administer orally with or without food. Use an accurate measuring device (e.g., oral syringe) provided with the medication.
Mechanism of Action
Azithromycin works by inhibiting bacterial protein synthesis. It binds to the 50S ribosomal subunit of susceptible microorganisms, thereby interfering with the translocation of peptides.
Pharmacokinetics
Onset
Clinical effects typically observed within 2-3 days of initiation.
Excretion
Mainly excreted unchanged in bile; a small amount is excreted in urine.
Half life
Terminal elimination half-life is 2-4 days.
Absorption
Rapidly absorbed from the gastrointestinal tract; bioavailability is approximately 37%.
Metabolism
Primarily metabolized in the liver, but a significant portion is excreted unchanged.
Side Effects
Contraindications
- •Hypersensitivity to azithromycin, erythromycin, or any macrolide or ketolide antibiotic
- •History of cholestatic jaundice/hepatic dysfunction associated with prior azithromycin use
Drug Interactions
Warfarin
Increased anticoagulant effect; monitor PT/INR closely.
Nelfinavir
Increased azithromycin concentrations.
Antacids (containing aluminum or magnesium)
Decreased peak serum levels of azithromycin. Administer azithromycin at least 1 hour before or 2 hours after antacids.
QT prolonging drugs (e.g., amiodarone, quinidine)
Increased risk of cardiac arrhythmias. Avoid co-administration if possible.
Storage
Store dry powder below 30°C, protected from light and moisture. After reconstitution, store at room temperature (15-30°C) and discard unused portion after the specified period (e.g., 5-10 days).
Overdose
Symptoms of overdose include severe nausea, vomiting, diarrhea, and reversible hearing loss. Management involves symptomatic and supportive measures. Gastric lavage and activated charcoal may be considered soon after ingestion.
Pregnancy & Lactation
Pregnancy Category B. Studies in animals have not shown harm to the fetus. Use during pregnancy only if clearly needed. Excreted in breast milk; use with caution in breastfeeding mothers, weighing potential risks vs. benefits.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 months for dry powder; 5-10 days once reconstituted, stored at room temperature.
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by major regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available (original patent expired)
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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