Azimon
Generic Name
Azithromycin
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| azimon 500 mg tablet | ৳ 35.00 | N/A |
Description
Overview of the medicine
Azithromycin is a macrolide antibiotic used to treat a wide variety of bacterial infections, including respiratory tract infections, skin and soft tissue infections, and certain sexually transmitted diseases.
Uses & Indications
Dosage
Adults
For most infections: 500 mg once daily for 3 days, or 500 mg as a single dose on day 1, followed by 250 mg once daily for 4 days.
Elderly
No specific dose adjustment is required for elderly patients unless severe renal or hepatic impairment is present.
Renal_impairment
No dose adjustment is needed in mild to moderate renal impairment. Caution is advised in severe renal impairment.
How to Take
Azimon-500-mg-tablet should be taken orally, with or without food. If taking antacids, Azimon should be taken at least 1 hour before or 2 hours after the antacid.
Mechanism of Action
Azithromycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of susceptible microorganisms, thereby interfering with the translocation of peptides.
Pharmacokinetics
Onset
Peak plasma concentrations are reached within 2-3 hours.
Excretion
Primarily excreted unchanged in bile; a small amount is excreted via urine.
Half life
Terminal elimination half-life is 2 to 4 days.
Absorption
Rapidly absorbed from the gastrointestinal tract; bioavailability is approximately 37%.
Metabolism
Extensively metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- •Hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic, or any component of the formulation.
- •History of cholestatic jaundice/hepatic dysfunction associated with prior azithromycin use.
Drug Interactions
Antacids
Aluminum and magnesium-containing antacids can reduce the peak plasma levels of azithromycin; administer Azithromycin at least 1 hour before or 2 hours after antacids.
Warfarin
Concurrent use may increase the anticoagulant effect of warfarin, requiring monitoring of INR.
Nelfinavir
Coadministration with nelfinavir may increase azithromycin serum concentrations.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose typically include nausea, vomiting, diarrhea, and reversible hearing loss. Management involves gastric lavage and general supportive and symptomatic measures.
Pregnancy & Lactation
Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus. However, there are no adequate and well-controlled studies in pregnant women. Use during pregnancy only if clearly needed. Azithromycin is excreted in human breast milk; caution should be exercised when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years from the date of manufacture when stored correctly.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
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Global Brand Names
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