Bactacef
Generic Name
Cefalexin
Manufacturer
Aristopharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| bactacef 500 mg capsule | ৳ 12.50 | ৳ 50.00 |
Description
Overview of the medicine
Cefalexin is a first-generation cephalosporin antibiotic used to treat a variety of bacterial infections.
Uses & Indications
Dosage
Adults
250 mg to 1 g every 6 hours, depending on the severity of infection. Max 4 g/day.
Elderly
Dosage adjustment may be necessary in elderly patients with reduced renal function.
Renal_impairment
Dosage reduction is required. e.g., Creatinine clearance 10-50 mL/min: 500 mg every 8-12 hours; <10 mL/min: 250 mg every 12 hours.
How to Take
Take orally with or without food. Complete the full course of medication even if symptoms improve.
Mechanism of Action
Cefalexin is a bactericidal antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs).
Pharmacokinetics
Onset
Approximately 1 hour
Excretion
Primarily by the kidneys via glomerular filtration and tubular secretion.
Half life
Approximately 1-1.5 hours in adults with normal renal function.
Absorption
Rapidly and well absorbed from the gastrointestinal tract.
Metabolism
Minimally metabolized; primarily excreted unchanged.
Side Effects
Contraindications
- •Hypersensitivity to cefalexin or any other cephalosporin antibiotics
- •History of severe hypersensitivity reaction to any beta-lactam antibiotic (e.g., penicillin)
Drug Interactions
Metformin
Cefalexin may increase metformin plasma concentrations.
Probenecid
May increase cefalexin levels by decreasing renal excretion.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, epigastric distress, diarrhea, and hematuria. Treatment is primarily supportive; hemodialysis may be considered in severe cases.
Pregnancy & Lactation
Cefalexin is generally considered safe during pregnancy (Category B). Small amounts are excreted in breast milk; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by regulatory authorities
Patent Status
Generic available
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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