Take orally, once daily in the morning with or without food. Swallow the tablet whole with water.

Bisoprolol is a highly selective beta1-adrenergic receptor blocker. It decreases heart rate and cardiac output, thereby lowering blood pressure. It also reduces myocardial oxygen demand.

• •Acute heart failure or during episodes of decompensation of heart failure requiring intravenous inotropic therapy
• •Cardiogenic shock
• •Sick sinus syndrome (unless a pacemaker is in situ)
• •Severe bradycardia (<50 bpm)
• •Severe hypotension
• •Severe bronchial asthma or severe chronic obstructive pulmonary disease (COPD)
• •Peripheral arterial occlusive disease and Raynaud's syndrome (severe forms)
• •Phaeochromocytoma (unless pre-treated with alpha-blockers)
• •Metabolic acidosis

Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.

Symptoms include bradycardia, hypotension, bronchospasm, and acute heart failure. Treatment is symptomatic and supportive. May involve atropine for bradycardia, vasopressors for hypotension, and bronchodilators for bronchospasm.

Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Bisoprolol is excreted in human milk; caution should be exercised when administered to a nursing mother.