Besone
Generic Name
Betamethasone
Manufacturer
Popular Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| besone 01 ointment | ৳ 13.04 | N/A |
Description
Overview of the medicine
Betamethasone is a potent corticosteroid used to reduce inflammation and itching caused by various skin conditions like eczema, psoriasis, and dermatitis.
Uses & Indications
Dosage
Adults
Apply a thin layer to the affected area once or twice daily.
Elderly
Same as adults, but with caution and for short durations.
Renal_impairment
No specific dosage adjustment for topical use.
How to Take
For topical use only. Wash hands before and after application. Do not cover the treated area with occlusive dressings unless advised by a doctor.
Mechanism of Action
Betamethasone acts by inhibiting phospholipase A2, leading to decreased synthesis of inflammatory mediators like prostaglandins and leukotrienes. It also suppresses immune responses.
Pharmacokinetics
Onset
Rapid relief of symptoms, usually within hours to days.
Excretion
Primarily via urine and bile.
Half life
Not well-defined for topical, systemic half-life is around 300-360 minutes.
Absorption
Systemic absorption can occur, especially with prolonged use, occlusive dressings, or application to large surface areas.
Metabolism
Primarily in the liver.
Side Effects
Contraindications
- •Hypersensitivity to betamethasone or any component.
- •Untreated skin infections (viral, bacterial, fungal).
- •Rosacea, acne vulgaris, perioral dermatitis.
Drug Interactions
0
No significant systemic drug interactions for topical use.
1
Can interact with other topical medications if applied concurrently (e.g., increased absorption or altered efficacy).
Storage
Store below 30°C in a dry place, away from light. Do not freeze.
Overdose
Topical overdose is rare, but chronic overuse can lead to signs of hypercorticism (e.g., Cushing's syndrome) and HPA axis suppression. Treatment is symptomatic.
Pregnancy & Lactation
Use during pregnancy and lactation only if the potential benefit outweighs the potential risk. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, Hospitals
Approval Status
Approved by major regulatory bodies globally
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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