Bilaben
Generic Name
bilastine
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Description
Overview of the medicine
Bilaben (Bilastine) is a non-sedating H1-antihistamine used for the symptomatic treatment of allergic rhinoconjunctivitis (seasonal and perennial) and urticaria.
Uses & Indications
Dosage
Adults
20 mg once daily
Elderly
No dose adjustment needed
Renal_impairment
No dose adjustment needed
How to Take
Oral, once daily. Take one hour before or two hours after food or fruit juice.
Mechanism of Action
Bilastine is a selective H1-receptor antagonist. It prevents histamine from binding to H1 receptors, thereby inhibiting the histamine-mediated effects like itching, sneezing, and runny nose.
Pharmacokinetics
Onset
Within 30-60 minutes
Excretion
Mainly via feces (approximately 67%) and urine (approximately 33%) as unchanged drug.
Half life
Approximately 14.5 hours
Absorption
Rapidly absorbed after oral administration; bioavailability is approximately 61%.
Metabolism
Minimally metabolized; primarily excreted unchanged.
Side Effects
Contraindications
- •Hypersensitivity to bilastine or any excipients
Drug Interactions
P-glycoprotein inhibitors
Caution with co-administration.
Ketoconazole, Erythromycin, Diltiazem
May increase plasma concentration of bilastine.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
No specific antidote. Symptomatic and supportive treatment is recommended. Gastric lavage may be considered.
Pregnancy & Lactation
Limited data available. Use during pregnancy only if clearly needed. Excretion into breast milk is unknown; caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Pharmacies, hospitals
Approval Status
Approved by health authorities in various countries (e.g., EMA, DGDA)
Patent Status
Patent expired or nearing expiry in some regions, generic versions available
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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