Bilanex
Generic Name
Bilastine Oral Solution
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| bilanex 125 mg oral solution | ৳ 140.00 | N/A |
Description
Overview of the medicine
Bilanex oral solution contains Bilastine, a second-generation antihistamine, used for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria. It provides relief from symptoms such as sneezing, runny nose, itchy eyes, and hives.
Uses & Indications
Dosage
Adults
Not typically recommended for adults; adults usually use 20 mg tablets. For children aged 6-11 years, the recommended dose is 10 mg (4 ml of oral solution) once daily.
Elderly
No dose adjustment is required for elderly patients taking oral solutions (if applicable).
Renal_impairment
No dose adjustment is required in patients with renal impairment.
How to Take
Administer orally. The solution should be taken one hour before or two hours after food or fruit juice. Do not mix with food or fruit juice.
Mechanism of Action
Bilastine is a non-sedating, long-acting histamine H1 receptor antagonist. It selectively binds to peripheral H1 receptors, thereby inhibiting the effects of histamine and reducing allergic symptoms. It also inhibits histamine-induced wheal and flare responses.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Approximately 95% excreted via urine (28%) and feces (67%) as unchanged drug.
Half life
Approximately 14.5 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached in approximately 1.3 hours. Bioavailability is about 61%.
Metabolism
Not significantly metabolized in humans. Primarily excreted unchanged.
Side Effects
Contraindications
- Hypersensitivity to the active substance Bilastine or to any of the excipients.
Drug Interactions
Diltiazem
Increases Bilastine plasma concentrations.
Erythromycin
Increases Bilastine plasma concentrations.
Ketoconazole
Increases Bilastine plasma concentrations.
Grapefruit juice
Reduces Bilastine oral bioavailability.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic treatment and supportive measures should be initiated. There is no specific antidote for Bilastine.
Pregnancy & Lactation
Use during pregnancy is not recommended unless clearly necessary. Caution should be exercised when prescribing to lactating women as it is unknown if Bilastine is excreted in human milk.
Side Effects
Contraindications
- Hypersensitivity to the active substance Bilastine or to any of the excipients.
Drug Interactions
Diltiazem
Increases Bilastine plasma concentrations.
Erythromycin
Increases Bilastine plasma concentrations.
Ketoconazole
Increases Bilastine plasma concentrations.
Grapefruit juice
Reduces Bilastine oral bioavailability.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic treatment and supportive measures should be initiated. There is no specific antidote for Bilastine.
Pregnancy & Lactation
Use during pregnancy is not recommended unless clearly necessary. Caution should be exercised when prescribing to lactating women as it is unknown if Bilastine is excreted in human milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months when unopened. Refer to the product packaging for specific dates.
Availability
Pharmacies, Hospitals
Approval Status
Approved (e.g., EU, Bangladesh)
Patent Status
Patent protected (brand specific), generics available in some regions
Clinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of Bilastine in the treatment of allergic rhinoconjunctivitis and urticaria across various age groups, showing similar efficacy to other second-generation antihistamines with a favorable safety profile.
Lab Monitoring
- No specific laboratory monitoring is typically required for routine Bilastine use.
Doctor Notes
- Emphasize the importance of taking the solution on an empty stomach for optimal efficacy.
- Advise parents on proper dosing for children using the provided measuring device.
- Reassure patients about its non-sedating profile compared to older antihistamines.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor.
- Do not exceed the recommended dose.
- Take on an empty stomach, at least one hour before or two hours after food or fruit juice.
- Shake the bottle well before each use.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Bilastine generally has low sedative properties, but individual reactions may vary. Patients should be advised not to drive or operate machinery until they know how they react to Bilastine.
Lifestyle Advice
- Avoid alcohol consumption as it may enhance drowsiness, although Bilastine has low sedative properties.
- Identify and avoid known allergens to help manage symptoms.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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