Bilfast
Generic Name
Fexofenadine Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| bilfast 125 mg oral solution | ৳ 90.00 | N/A |
Description
Overview of the medicine
Bilfast 125 mg Oral Solution contains Fexofenadine Hydrochloride, a non-drowsy antihistamine used to relieve symptoms of seasonal allergic rhinitis and chronic idiopathic urticaria.
Uses & Indications
Dosage
Adults
The usual adult dose for allergic rhinitis is 60 mg twice daily or 120-180 mg once daily. For chronic urticaria, 60 mg twice daily or 180 mg once daily. For Bilfast 125 mg oral solution, follow physician's instruction, possibly 125 mg once or twice daily.
Elderly
No dosage adjustment is generally required for elderly patients unless they have impaired renal function.
Renal_impairment
For patients with impaired renal function, a starting dose of 60 mg once daily is recommended. For 125 mg oral solution, a reduced frequency/dose should be considered as per physician's advice.
How to Take
Bilfast Oral Solution is for oral use. It can be taken with or without food. Use the provided measuring device to ensure accurate dosing.
Mechanism of Action
Fexofenadine is a selective peripheral H1-receptor antagonist. It competitively inhibits the binding of histamine to H1 receptors, thereby preventing the effects of histamine such as itching, sneezing, and runny nose.
Pharmacokinetics
Onset
Onset of action is approximately 1 hour.
Excretion
Primarily excreted unchanged, with about 80% recovered in feces and 10% in urine.
Half life
The elimination half-life is approximately 11-15 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached in approximately 1-3 hours.
Metabolism
Minimally metabolized in the liver (approximately 5-10% of the dose).
Side Effects
Contraindications
- Known hypersensitivity to fexofenadine or any of the excipients in the formulation.
Drug Interactions
Erythromycin and Ketoconazole
Can increase plasma concentrations of fexofenadine. No dosage adjustment is generally necessary, but monitor for increased side effects.
Antacids (containing aluminum or magnesium)
Concurrent use can reduce fexofenadine absorption. Separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Do not freeze.
Overdose
Symptoms of overdose include drowsiness, dizziness, and dry mouth. Management is symptomatic and supportive; there is no specific antidote.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in breast milk; use with caution in nursing mothers.
Side Effects
Contraindications
- Known hypersensitivity to fexofenadine or any of the excipients in the formulation.
Drug Interactions
Erythromycin and Ketoconazole
Can increase plasma concentrations of fexofenadine. No dosage adjustment is generally necessary, but monitor for increased side effects.
Antacids (containing aluminum or magnesium)
Concurrent use can reduce fexofenadine absorption. Separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Do not freeze.
Overdose
Symptoms of overdose include drowsiness, dizziness, and dry mouth. Management is symptomatic and supportive; there is no specific antidote.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted in breast milk; use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 to 36 months when stored under recommended conditions.
Availability
Pharmacies, hospitals in Bangladesh
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Generics available, patent expired
Clinical Trials
Fexofenadine has been extensively studied in numerous clinical trials, demonstrating efficacy and a favorable safety profile for the treatment of seasonal allergic rhinitis and chronic idiopathic urticaria across various age groups.
Lab Monitoring
- No routine laboratory monitoring is generally required for fexofenadine.
Doctor Notes
- Emphasize to patients the importance of avoiding concomitant administration with aluminum- or magnesium-containing antacids.
- Advise patients regarding the potential interaction with fruit juices and recommend separating intake.
Patient Guidelines
- Take Bilfast exactly as prescribed by your doctor.
- Do not exceed the recommended dose.
- Avoid consuming fruit juices around the time of taking this medicine.
- Inform your doctor or pharmacist about all medications and supplements you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Fexofenadine is generally non-sedating, but individual responses can vary. Exercise caution when driving or operating machinery until you know how this medicine affects you.
Lifestyle Advice
- Identify and avoid known allergens to help manage your symptoms.
- Maintain good hydration by drinking plenty of fluids.
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Global Brand Names
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