Blast
Generic Name
blast-10-mg-tablet
Manufacturer
PharmaCorp Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| blast 10 mg tablet | ৳ 15.00 | ৳ 150.00 |
Description
Overview of the medicine
Blast 10 mg Tablet is a medication used to relieve pain and reduce inflammation in various conditions such as arthritis, musculoskeletal pain, and menstrual cramps.
Uses & Indications
Dosage
Adults
10 mg once daily, or as directed by physician. Max 20 mg/day.
Elderly
Initial dose 5 mg once daily, adjust based on renal function.
Renal_impairment
Use with caution. Dosage reduction may be required. Not recommended for severe impairment.
How to Take
Take orally with food or milk to minimize gastrointestinal upset.
Mechanism of Action
Blast 10 mg inhibits the activity of cyclooxygenase (COX) enzymes, particularly COX-2, which are responsible for the synthesis of prostaglandins, mediators of pain and inflammation.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Mainly through urine as metabolites.
Half life
Approximately 8-12 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract.
Metabolism
Primarily hepatic metabolism via CYP450 enzymes.
Side Effects
Contraindications
- Hypersensitivity to the active ingredient or other NSAIDs
- History of gastrointestinal bleeding or ulceration
- Severe renal or hepatic impairment
- Severe heart failure
- Third trimester of pregnancy
Drug Interactions
Lithium
Increased plasma lithium levels.
Warfarin
Increased risk of bleeding.
Diuretics
Reduced diuretic and antihypertensive effects.
Storage
Store below 30°C in a dry place, away from direct sunlight.
Overdose
Symptoms may include nausea, vomiting, epigastric pain, lethargy, drowsiness. Management involves symptomatic and supportive care. Gastric lavage or activated charcoal may be considered.
Pregnancy & Lactation
Not recommended during the third trimester of pregnancy due to risk of premature closure of the ductus arteriosus. Use with caution during lactation; consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to the active ingredient or other NSAIDs
- History of gastrointestinal bleeding or ulceration
- Severe renal or hepatic impairment
- Severe heart failure
- Third trimester of pregnancy
Drug Interactions
Lithium
Increased plasma lithium levels.
Warfarin
Increased risk of bleeding.
Diuretics
Reduced diuretic and antihypertensive effects.
Storage
Store below 30°C in a dry place, away from direct sunlight.
Overdose
Symptoms may include nausea, vomiting, epigastric pain, lethargy, drowsiness. Management involves symptomatic and supportive care. Gastric lavage or activated charcoal may be considered.
Pregnancy & Lactation
Not recommended during the third trimester of pregnancy due to risk of premature closure of the ductus arteriosus. Use with caution during lactation; consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Active Patent
Clinical Trials
Ongoing post-marketing surveillance for long-term safety and efficacy.
Lab Monitoring
- Regular monitoring of renal function, liver function, and complete blood count (CBC) is recommended during long-term therapy.
Doctor Notes
- Prescribe at the lowest effective dose for the shortest duration consistent with patient treatment goals.
- Monitor for signs of GI bleeding or cardiovascular adverse events.
- Advise patients on proper administration and potential side effects.
Patient Guidelines
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
- Report any signs of gastrointestinal bleeding immediately.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Driving Precautions
May cause dizziness or drowsiness; use caution when driving or operating machinery.
Lifestyle Advice
- Avoid excessive alcohol consumption. Maintain a healthy diet and stay hydrated.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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