Bredox
Generic Name
Cefixime
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| bredox 400 mg tablet | ৳ 8.00 | ৳ 56.00 |
Description
Overview of the medicine
Bredox 400 mg Tablet is an antibiotic from the cephalosporin class, used to treat a wide variety of bacterial infections. It works by stopping the growth of bacteria.
Uses & Indications
Dosage
Adults
400 mg once daily or 200 mg every 12 hours.
Elderly
No specific dose adjustment required unless severe renal impairment.
Renal_impairment
Adjust dosage based on creatinine clearance; e.g., if CrCl < 60 mL/min, reduce dose.
How to Take
Take orally with or without food. Can be taken with food to reduce gastrointestinal upset.
Mechanism of Action
Cefixime is a bactericidal antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and death.
Pharmacokinetics
Onset
Not specified, but generally within a few hours for antibiotic effect.
Excretion
Primarily excreted unchanged in the urine, with some biliary excretion.
Half life
Approximately 3-4 hours.
Absorption
Approximately 40-50% absorbed from the gastrointestinal tract; absorption is slightly higher with food.
Metabolism
Not extensively metabolized in the liver; some hepatic metabolism may occur.
Side Effects
Contraindications
- •Hypersensitivity to Cefixime or other cephalosporins
- •History of anaphylactic reaction to penicillin
Drug Interactions
Warfarin
May increase prothrombin time (INR); monitor closely.
Oral Contraceptives
May reduce efficacy of oral contraceptives; use alternative contraception.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Gastric lavage may be indicated; otherwise, treatment is symptomatic and supportive. Hemodialysis or peritoneal dialysis does not effectively remove Cefixime from the body.
Pregnancy & Lactation
Pregnancy category B. Use only if clearly needed during pregnancy. Small amounts excreted in breast milk; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic (Patent Expired)
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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