Butacit
Generic Name
Butamirate Citrate
Manufacturer
Acme Laboratories Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| butacit 75 mg syrup | ৳ 80.00 | N/A |
| butacit 5 mg pediatric drop | ৳ 50.00 | N/A |
Description
Overview of the medicine
Butamirate Citrate is a non-opioid antitussive agent used for symptomatic treatment of coughs of various etiologies. It acts directly on the cough center, helping to suppress both dry and productive coughs.
Uses & Indications
Dosage
Adults
15 ml (22.5 mg) 3-4 times daily.
Elderly
Same as adult dose, adjust if renal/hepatic impairment.
Renal_impairment
Use with caution, dose adjustment may be required.
How to Take
Oral administration. Take with or without food. Measure dose accurately using the provided measuring cup or spoon.
Mechanism of Action
Butamirate Citrate acts directly on the cough center in the medulla oblongata, suppressing the cough reflex. It also exhibits a bronchodilating effect and reduces airway resistance.
Pharmacokinetics
Onset
Within 30 minutes to 1 hour.
Excretion
Mainly excreted via the kidneys, primarily as metabolites.
Half life
Approximately 4-6 hours (for metabolites).
Absorption
Rapidly and completely absorbed from the gastrointestinal tract.
Metabolism
Undergoes hydrolysis to two main metabolites, 2-phenylbutyric acid and diethylaminoethoxyethanol, which also have antitussive activity.
Side Effects
Contraindications
- Hypersensitivity to Butamirate Citrate or any component of the formulation
- Children under 2 months (for drops) or 2 years (for syrup/tablets)
Drug Interactions
Expectorants
Avoid concomitant use as it may lead to accumulation of secretions in the airways.
Central nervous system depressants
May enhance CNS depressant effects.
Storage
Store below 30°C in a dry place, away from light. Do not freeze.
Overdose
Symptoms may include drowsiness, nausea, vomiting, diarrhea, dizziness, and hypotension. Treatment is symptomatic and supportive, including gastric lavage and activated charcoal if overdose is recent.
Pregnancy & Lactation
Limited data available. Use during pregnancy only if clearly needed and benefits outweigh risks. Caution is advised during lactation as it is unknown if Butamirate Citrate passes into breast milk.
Side Effects
Contraindications
- Hypersensitivity to Butamirate Citrate or any component of the formulation
- Children under 2 months (for drops) or 2 years (for syrup/tablets)
Drug Interactions
Expectorants
Avoid concomitant use as it may lead to accumulation of secretions in the airways.
Central nervous system depressants
May enhance CNS depressant effects.
Storage
Store below 30°C in a dry place, away from light. Do not freeze.
Overdose
Symptoms may include drowsiness, nausea, vomiting, diarrhea, dizziness, and hypotension. Treatment is symptomatic and supportive, including gastric lavage and activated charcoal if overdose is recent.
Pregnancy & Lactation
Limited data available. Use during pregnancy only if clearly needed and benefits outweigh risks. Caution is advised during lactation as it is unknown if Butamirate Citrate passes into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from the manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Off-patent
Clinical Trials
Clinical trials have shown Butamirate Citrate to be effective in reducing cough frequency and intensity with a good safety profile.
Lab Monitoring
- No specific lab monitoring required.
Doctor Notes
- Butamirate Citrate is a centrally acting antitussive.
- Effective for both dry and irritating coughs.
- Consider advising patients about potential drowsiness.
Patient Guidelines
- Do not exceed the recommended dose.
- Inform your doctor if cough persists for more than 7 days.
- Keep out of reach of children.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
May cause drowsiness or dizziness. Exercise caution when driving or operating machinery.
Lifestyle Advice
- Maintain adequate hydration.
- Avoid irritants like smoke and dust.
- Get sufficient rest.
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