Medicine Information

Butacit

Name: Butacit
Brand: Butacit
Rating: 4.5 (117 reviews)

Syrup75 mg (total Butamirate Citrate in a standard bottle, e.g., 60 ml)Antitussive, Non-opioidATC: R05DB13

Generic Name

butacit-75-mg-syrup

Manufacturer

Incepta Pharmaceuticals Ltd.

Country

Bangladesh

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Price Details

Current market pricing information

Variant	Unit Price	Strip Price
butacit 75 mg syrup	৳ 80.00	N/A

Description

Overview of the medicine

Butacit syrup contains Butamirate Citrate, a non-opioid antitussive agent used for the symptomatic treatment of coughs of various etiologies. It helps to reduce the frequency and intensity of coughing.

Uses & Indications

Symptomatic treatment of cough of various etiologies

Acute cough

Pre- and post-operative cough suppression (e.g., for bronchoscopy)

Whooping cough

Dosage

Adults

Assuming 75 mg total in a 60 ml bottle (1.25 mg/ml): 15-20 ml (approx. 18.75-25 mg) 3-4 times daily. Consult product leaflet for specific concentration and dosage.

Elderly

Same as adult dosage, or adjust based on clinical condition. Consult product leaflet for specific concentration and dosage.

Renal_impairment

No specific dose adjustment is usually required, but use with caution in severe impairment. Consult a physician.

How to Take

For oral administration. Measure the prescribed dose using the provided measuring cup or spoon.

Mechanism of Action

Butamirate Citrate is believed to exert its antitussive action by selectively depressing the cough reflex in the brainstem, without affecting the respiratory center. It also possesses some bronchodilatory effects.

Pharmacokinetics

Onset

Within 30 minutes

Excretion

Mainly via the kidneys, primarily as metabolites.

Half life

Approximately 4 hours

Absorption

Rapidly and completely absorbed from the gastrointestinal tract. Peak plasma concentrations are reached within 1-2 hours.

Metabolism

Hydrolyzed to 2-phenylbutyric acid and diethylaminoethoxyethanol, which are also active.

Side Effects

Contraindications

Hypersensitivity to Butamirate Citrate or any component of the syrup
Children under 3 years of age (for specific formulations, check leaflet)

Drug Interactions

Other CNS depressants

May enhance CNS depression if used concomitantly, though unlikely with Butamirate Citrate.

Expectorants/Mucolytics

Concurrent use may lead to mucus retention in the respiratory tract due to suppressed cough reflex. Avoid co-administration.

Storage

Store below 30°C in a dry place, away from direct sunlight and moisture. Do not freeze.

Overdose

Symptoms of overdose may include drowsiness, nausea, vomiting, diarrhea, and dizziness. In case of overdose, seek immediate medical attention. Management is symptomatic and supportive, including gastric lavage and activated charcoal if appropriate.

Pregnancy & Lactation

Pregnancy Category C. Use only if clearly needed and the potential benefit outweighs the potential risk to the fetus. It is unknown if Butamirate Citrate is excreted in breast milk; use with caution during lactation.

Frequently Asked Questions

Common questions about this medicine

Pack Sizes

60 ml bottle100 ml bottle

Shelf Life

2-3 years from manufacturing date (check specific product for exact date)

Availability

Pharmacies, Drugstores

Approval Status

Approved in many countries

Patent Status

Expired

Clinical Trials

Butamirate Citrate has been studied in various clinical trials demonstrating its efficacy and safety as an antitussive agent in both adult and pediatric populations.

Lab Monitoring

No specific laboratory monitoring is typically required for Butamirate Citrate.

Doctor Notes

Advise patients on proper measurement of syrup to avoid under- or over-dosing.
Counsel patients on when to seek further medical attention (e.g., persistent cough, fever).
Avoid concurrent use with expectorants/mucolytics.

Patient Guidelines

Always measure the dose accurately using the provided measuring device.
Do not exceed the recommended dose.
If cough persists for more than 7 days, worsens, or is accompanied by fever, rash, or persistent headache, consult a doctor.
Keep out of reach of children.

Missed Dose Advice

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.