Cefadyl DS
Generic Name
Cephradine
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| cefadyl ds 200 mg suspension | ৳ 300.00 | N/A |
Description
Overview of the medicine
Cefadyl DS contains Cephradine, a first-generation cephalosporin antibiotic, used to treat a variety of bacterial infections.
Uses & Indications
Dosage
Adults
250-500 mg every 6-12 hours, up to 4 g/day for severe infections. For Cefadyl DS 500mg, typical adult dose is 500mg twice daily.
Elderly
Adjust dose based on renal function.
Renal_impairment
Dose reduction necessary; e.g., CrCl 10-25 mL/min: 250 mg every 12 hours.
How to Take
Can be taken with or without food. Take with food if stomach upset occurs.
Mechanism of Action
Cephradine works by inhibiting bacterial cell wall synthesis, leading to bacterial lysis and death. It binds to penicillin-binding proteins (PBPs).
Pharmacokinetics
Onset
Not well-defined, generally within hours.
Excretion
Primarily via renal excretion (glomerular filtration and tubular secretion).
Half life
Approximately 0.75-1.5 hours.
Absorption
Rapidly and well absorbed from the gastrointestinal tract.
Metabolism
Minimally metabolized; primarily excreted unchanged.
Side Effects
Contraindications
- •Hypersensitivity to cephalosporins or penicillins
- •Severe renal impairment without dose adjustment
Drug Interactions
Probenecid
Increases cephradine levels.
Oral anticoagulants
May potentiate anticoagulant effects.
Nephrotoxic drugs (e.g., aminoglycosides)
Increased risk of nephrotoxicity.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, diarrhea, epigastric distress. Treatment is largely supportive; hemodialysis may be useful in severe cases.
Pregnancy & Lactation
Category B in pregnancy. Use with caution during lactation; small amounts excreted in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, hospitals
Approval Status
Approved by drug regulatory authorities (e.g., FDA, DGDA)
Patent Status
Off-patent
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Global Brand Names
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