Cefinaaf
Generic Name
Cefinaaf
Manufacturer
MediCorp Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| cefinaaf 100 mg suspension | ৳ 280.00 | N/A |
Description
Overview of the medicine
Cefinaaf 100 mg suspension is a broad-spectrum antibiotic belonging to the cephalosporin class, primarily used to treat various bacterial infections in children.
Uses & Indications
Dosage
Adults
Not typically used for adults in suspension form; adults usually require higher strength tablets (e.g., 200-400 mg).
Elderly
No specific dose adjustment needed unless severe renal impairment; consult physician.
Renal_impairment
Dosage reduction advised in severe renal impairment (CrCl < 30 mL/min). Consult physician.
How to Take
Oral administration. Shake the bottle well before each use. Can be taken with or without food. Complete the full course of treatment as prescribed.
Mechanism of Action
Cefinaaf is a bactericidal antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and death.
Pharmacokinetics
Onset
Within 1-2 hours
Excretion
Primarily renal (via glomerular filtration and tubular secretion).
Half life
Approximately 3-4 hours
Absorption
Well absorbed from the gastrointestinal tract; food may affect absorption rate but not extent.
Metabolism
Limited hepatic metabolism; primarily excreted unchanged.
Side Effects
Contraindications
- Hypersensitivity to cefinaaf or any other cephalosporin antibiotics.
- History of severe hypersensitivity reactions to penicillin or other beta-lactam antibiotics.
Drug Interactions
Probenecid
May increase cefinaaf plasma concentrations by inhibiting renal excretion.
Live Typhoid Vaccine
Antibiotics may reduce the therapeutic effect of live typhoid vaccine; administer at least 3 days apart.
Oral Anticoagulants (e.g., Warfarin)
May enhance the anticoagulant effect; monitor INR closely.
Storage
Store dry powder below 30°C, protected from light and moisture. After reconstitution, store suspension at room temperature (below 30°C) or in a refrigerator (2-8°C), depending on manufacturer's instructions. Do not freeze.
Overdose
In case of overdose, gastric lavage may be considered. No specific antidote. Symptomatic and supportive treatment is recommended. Hemodialysis is not considered effective.
Pregnancy & Lactation
Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus. Use during pregnancy only if clearly needed. Excreted in breast milk in small amounts; use with caution during lactation. Consult a physician.
Side Effects
Contraindications
- Hypersensitivity to cefinaaf or any other cephalosporin antibiotics.
- History of severe hypersensitivity reactions to penicillin or other beta-lactam antibiotics.
Drug Interactions
Probenecid
May increase cefinaaf plasma concentrations by inhibiting renal excretion.
Live Typhoid Vaccine
Antibiotics may reduce the therapeutic effect of live typhoid vaccine; administer at least 3 days apart.
Oral Anticoagulants (e.g., Warfarin)
May enhance the anticoagulant effect; monitor INR closely.
Storage
Store dry powder below 30°C, protected from light and moisture. After reconstitution, store suspension at room temperature (below 30°C) or in a refrigerator (2-8°C), depending on manufacturer's instructions. Do not freeze.
Overdose
In case of overdose, gastric lavage may be considered. No specific antidote. Symptomatic and supportive treatment is recommended. Hemodialysis is not considered effective.
Pregnancy & Lactation
Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus. Use during pregnancy only if clearly needed. Excreted in breast milk in small amounts; use with caution during lactation. Consult a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months (dry powder); 7-14 days after reconstitution when stored as directed.
Availability
Pharmacies nationwide
Approval Status
DGDA Approved
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
As a hypothetical drug in a well-established class, efficacy and safety are inferred from similar agents. Specific trials for 'Cefinaaf' would be required for market approval.
Lab Monitoring
- Renal function tests (e.g., creatinine, BUN) in patients with pre-existing renal impairment.
- Liver function tests (e.g., ALT, AST) if prolonged therapy or hepatic impairment.
- Complete Blood Count (CBC) for prolonged therapy.
Doctor Notes
- Counsel parents on proper administration and importance of completing the full course.
- Advise on potential for GI upset and appropriate management.
- Be vigilant for signs of hypersensitivity reactions, especially in penicillin-allergic patients.
Patient Guidelines
- Always complete the full course of antibiotics, even if symptoms improve.
- Do not save leftover medication for future infections.
- Consult a doctor if symptoms do not improve or worsen.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Generally, cefinaaf does not affect the ability to drive or operate machinery. However, if side effects like dizziness occur, avoid such activities.
Lifestyle Advice
- Maintain good hydration.
- Avoid self-medication.
- Ensure proper hygiene to prevent spread of infection.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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