Cetril tablet should be swallowed whole with a glass of water, with or without food. It can be taken at any time of day, but consistency in timing is recommended.

Cetirizine is a potent and selective antagonist of peripheral H1-receptors. It inhibits the histamine-induced early phase of allergic reactions and also reduces the migration of inflammatory cells and the release of mediators associated with the late phase of allergic reactions.

• •Known hypersensitivity to Cetirizine, hydroxyzine, or any piperazine derivatives
• •Patients with severe renal impairment (creatinine clearance <10 mL/min)

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.

Symptoms of overdose may include drowsiness, agitation, restlessness, and rarely, tachycardia. Treatment is symptomatic and supportive. Gastric lavage may be considered if ingestion is recent.

Pregnancy Category B. Studies in animals have not shown a risk to the fetus, but there are no adequate and well-controlled studies in pregnant women. Use during pregnancy only if clearly needed. Cetirizine is excreted in human breast milk; therefore, caution should be exercised when administered to a nursing woman.