Oral administration. May be taken with or without food. Use a measuring spoon or cup for accurate dosing.

Cetirizine is a potent and selective antagonist of peripheral H1-receptors. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms, thereby reducing allergic reactions like sneezing, runny nose, and itching.

• •Known hypersensitivity to cetirizine, hydroxyzine, or any piperazine derivative.
• •Patients with severe renal impairment (creatinine clearance less than 10 ml/min).

Store in a cool, dry place, below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.

Symptoms of overdose may include drowsiness, agitation, restlessness, and rarely, convulsions. Management is symptomatic and supportive. There is no specific antidote for cetirizine. Gastric lavage may be considered soon after ingestion.

Pregnancy Category B. Studies in animals have shown no evidence of harm to the fetus. However, use in pregnancy only if clearly needed and the potential benefits outweigh the potential risks. Cetirizine is excreted in breast milk; therefore, caution is advised when administered to a nursing woman.