Oral administration, with or without food. Can be taken in the morning or evening.

Cetirizine is a potent and selective antagonist of peripheral H1-receptors. It binds to H1-receptors, preventing histamine from binding and exerting its effects, thereby reducing allergic symptoms. Unlike first-generation antihistamines, it causes less sedation due to its poor ability to cross the blood-brain barrier.

• •Hypersensitivity to cetirizine or hydroxyzine
• •Severe renal impairment (creatinine clearance <10 mL/min)

Store below 30°C in a dry place, protected from light. Keep out of reach of children.

Symptoms include drowsiness, agitation in children. Management is supportive and symptomatic; no specific antidote.

Pregnancy Category B. Use only if clearly needed. Excreted in breast milk, use with caution during lactation.