Clarex
Generic Name
Desloratadine
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| clarex 5 mg tablet | ৳ 2.50 | ৳ 25.00 |
Description
Overview of the medicine
Clarex is an antihistamine used to relieve allergy symptoms such as sneezing, runny nose, watery eyes, and itching. It also treats hives and chronic idiopathic urticaria.
Uses & Indications
Dosage
Adults
Adults and adolescents 12 years and over: 5 mg once daily.
Elderly
No specific dosage adjustment recommended for elderly patients with normal renal function.
Renal_impairment
For patients with renal impairment, a starting dose of 5 mg every other day is recommended.
How to Take
May be taken with or without food. Swallow the tablet whole with water.
Mechanism of Action
Desloratadine is a selective peripheral histamine H1-receptor antagonist. It inhibits the release of histamine from mast cells and reduces inflammatory mediators, thereby alleviating allergy symptoms.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Primarily via urine and feces
Half life
Approximately 27 hours
Absorption
Rapidly absorbed after oral administration; peak plasma concentrations reached within approx. 3 hours.
Metabolism
Extensive metabolism to 3-hydroxydesloratadine, followed by glucuronide conjugation.
Side Effects
Contraindications
- Hypersensitivity to desloratadine, loratadine, or any component of the formulation.
- Known allergic reactions to similar antihistamines.
Drug Interactions
Cimetidine
Increased plasma concentration of desloratadine.
Erythromycin
Increased plasma concentration of desloratadine.
Ketoconazole
Increased plasma concentration of desloratadine.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In the event of an overdose, symptomatic and supportive treatment should be initiated. Desloratadine is not eliminated by hemodialysis.
Pregnancy & Lactation
Pregnancy: Category C. Use only if potential benefit justifies potential risk to the fetus. Lactation: Desloratadine is excreted in breast milk. Caution should be exercised when administered to a nursing woman.
Side Effects
Contraindications
- Hypersensitivity to desloratadine, loratadine, or any component of the formulation.
- Known allergic reactions to similar antihistamines.
Drug Interactions
Cimetidine
Increased plasma concentration of desloratadine.
Erythromycin
Increased plasma concentration of desloratadine.
Ketoconazole
Increased plasma concentration of desloratadine.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In the event of an overdose, symptomatic and supportive treatment should be initiated. Desloratadine is not eliminated by hemodialysis.
Pregnancy & Lactation
Pregnancy: Category C. Use only if potential benefit justifies potential risk to the fetus. Lactation: Desloratadine is excreted in breast milk. Caution should be exercised when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, hospitals
Approval Status
Approved by DGDA/FDA
Patent Status
Off-patent (generic available)
Clinical Trials
Numerous clinical trials have established the efficacy and safety of desloratadine for allergic rhinitis and chronic urticaria.
Doctor Notes
- Advise patients on proper administration and potential side effects.
- Consider renal dose adjustment for patients with impaired kidney function.
Patient Guidelines
- Take as directed by your doctor.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not double the dose.
Driving Precautions
Desloratadine generally causes minimal sedation. However, caution is advised when performing tasks requiring mental alertness, such as driving or operating machinery, until you know how this medication affects you.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Clarex Brand
Other medicines available under the same brand name
