Conate D
Generic Name
Betamethasone + Dexchlorpheniramine + Dexpanthenol
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| conate d 500 mg tablet | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Conate D cream is a combination medication used to treat various inflammatory skin conditions that are accompanied by itching and where secondary bacterial infection is a concern. It combines a corticosteroid (Betamethasone) to reduce inflammation, an antihistamine (Dexchlorpheniramine) to alleviate itching, and Dexpanthenol to promote skin healing and hydration.
Uses & Indications
Dosage
Adults
Apply a thin layer to affected area once or twice daily.
Elderly
No specific dose adjustment required, use with caution.
Renal_impairment
Not typically relevant for topical application unless extensive systemic absorption.
How to Take
For external use only. Apply a thin layer to the affected skin area and gently rub in. Do not apply to open wounds or mucous membranes.
Mechanism of Action
Betamethasone is a potent corticosteroid that suppresses inflammation, itching, and vasoconstriction. Dexchlorpheniramine is an antihistamine that blocks H1-receptors, reducing allergic symptoms like itching. Dexpanthenol is a vitamin B5 derivative that aids in skin repair and regeneration.
Pharmacokinetics
Onset
Local effects typically within hours.
Excretion
Renal excretion for systemic metabolites.
Half life
Not well-defined for topical use; systemic half-life of Betamethasone is several hours.
Absorption
Limited systemic absorption, increased with broken skin or occlusive dressings.
Metabolism
Primarily hepatic for systemically absorbed components.
Side Effects
Contraindications
- Hypersensitivity to any component
- Untreated fungal or viral skin infections
- Acne vulgaris
- Rosacea
- Perioral dermatitis
Drug Interactions
Systemic absorption
Systemic absorption could theoretically interact with other corticosteroids or antihistamines if significant amounts are absorbed.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause acute systemic effects. Chronic overuse may lead to local skin atrophy, striae, or systemic corticosteroid effects like Cushing's syndrome (rare).
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and potential benefits outweigh risks. Consult a doctor. Avoid extensive application or prolonged use.
Side Effects
Contraindications
- Hypersensitivity to any component
- Untreated fungal or viral skin infections
- Acne vulgaris
- Rosacea
- Perioral dermatitis
Drug Interactions
Systemic absorption
Systemic absorption could theoretically interact with other corticosteroids or antihistamines if significant amounts are absorbed.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause acute systemic effects. Chronic overuse may lead to local skin atrophy, striae, or systemic corticosteroid effects like Cushing's syndrome (rare).
Pregnancy & Lactation
Use during pregnancy and lactation only if clearly needed and potential benefits outweigh risks. Consult a doctor. Avoid extensive application or prolonged use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies nationwide
Approval Status
Approved
Patent Status
Generic available
Clinical Trials
Specific clinical trial data for this exact combination may be limited; trials typically focus on individual components.
Lab Monitoring
- Not typically required for topical application.
Doctor Notes
- Advise patients on proper application technique and duration.
- Monitor for signs of secondary infection or skin atrophy.
Patient Guidelines
- Apply sparingly
- Avoid contact with eyes
- Do not use for longer than prescribed
- Wash hands before and after application
Missed Dose Advice
If a dose is missed, apply it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not apply extra to make up for a missed dose.
Driving Precautions
No known effects on driving ability.
Lifestyle Advice
- Keep affected skin clean and dry
- Avoid irritants
- Wear loose clothing
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.