For external use only. Apply a thin film to the affected skin area and rub in gently. Wash hands thoroughly before and after application. Do not cover with occlusive dressings unless advised by a doctor.

Clobetasol Propionate acts as a potent corticosteroid, reducing inflammation, itching, and vasoconstriction. It achieves this by inducing phospholipase A2 inhibitory proteins, leading to a reduction in the biosynthesis of inflammatory mediators like prostaglandins and leukotrienes. Neomycin Sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, thereby exhibiting bactericidal action against a wide range of gram-negative and some gram-positive bacteria.

• •Hypersensitivity to Clobetasol Propionate, Neomycin Sulfate, or any component
• •Viral skin infections (e.g., herpes simplex, chickenpox)
• •Fungal infections of the skin
• •Tuberculosis of the skin
• •Acne vulgaris
• •Rosacea
• •Perioral dermatitis
• •Ulcerated skin conditions
• •Children under 1 year

Store below 25°C (77°F). Protect from light and moisture. Do not freeze. Keep out of reach of children.

Acute overdose with topical application is unlikely. Chronic overuse or use on large areas/occlusive dressings may lead to systemic corticosteroid effects (e.g., Cushing's syndrome, HPA axis suppression) or local adverse effects. Neomycin systemic absorption from large areas of damaged skin may lead to ototoxicity or nephrotoxicity. Treatment is symptomatic and supportive; gradual withdrawal of the corticosteroid may be needed.

Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Clobetasol and Neomycin are excreted in breast milk; use with caution in breastfeeding mothers. Consult a doctor before use.