Debocal
Generic Name
Calcium Carbonate + Vitamin D3
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| debocal 500 mg tablet | ৳ 10.00 | N/A |
Description
Overview of the medicine
Debocal is a combination medicine containing Calcium Carbonate and Vitamin D3 (Cholecalciferol), primarily used for the prevention and treatment of calcium and vitamin D deficiencies, bone health, and conditions like osteoporosis.
Uses & Indications
Dosage
Adults
1-2 tablets daily, or as directed by physician. Should be taken with meals.
Elderly
Same as adults, or as advised by physician, particularly if renal function is impaired.
Renal_impairment
Caution advised; dosage adjustment may be necessary. Not recommended for severe renal failure.
How to Take
Oral. Take with a glass of water, preferably with meals to enhance absorption and reduce gastric upset.
Mechanism of Action
Calcium is essential for bone formation and maintenance, muscle contraction, nerve function, and blood coagulation. Vitamin D3 helps in the absorption of calcium and phosphate from the intestine and regulates their metabolism, thus playing a crucial role in bone mineralization.
Pharmacokinetics
Onset
Long-term effect, not immediate
Excretion
Calcium: primarily via feces (unabsorbed) and kidneys. Vitamin D3: primarily via bile and feces.
Half life
Calcium: variable; Vitamin D3: 2-3 days (parent compound), active metabolites much longer.
Absorption
Calcium is absorbed primarily in the small intestine, absorption rate varies. Vitamin D3 is absorbed from the small intestine, primarily in the jejunum.
Metabolism
Calcium is not metabolized. Vitamin D3 is hydroxylated in the liver to 25-hydroxyvitamin D (calcifediol) and then in the kidneys to 1,25-dihydroxyvitamin D (calcitriol), the active form.
Side Effects
Contraindications
- •Hypersensitivity to calcium or vitamin D
- •Hypercalcemia
- •Severe renal impairment
- •Hypercalciuria
- •Nephrolithiasis (kidney stones)
- •Hypervitaminosis D
Drug Interactions
Bisphosphonates
Calcium can interfere with absorption. Take calcium at least 30 minutes after bisphosphonates.
Corticosteroids
Can decrease calcium absorption.
Thyroid hormones
Calcium can reduce absorption of levothyroxine. Separate by at least 4 hours.
Thiazide diuretics
May increase risk of hypercalcemia.
Digitalis glycosides
Hypercalcemia can potentiate digitalis toxicity.
Tetracyclines/Quinolones
Calcium can reduce absorption of these antibiotics. Separate administration by at least 2-4 hours.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include hypercalcemia, nausea, vomiting, constipation, thirst, polyuria, anorexia, fatigue, and muscle weakness. Severe overdose can lead to renal impairment, cardiac arrhythmias, and coma. Treatment involves discontinuation of the drug, hydration, and management of hypercalcemia (e.g., loop diuretics, corticosteroids).
Pregnancy & Lactation
Generally considered safe and often recommended during pregnancy and lactation for adequate calcium and vitamin D intake, but should be used under medical supervision.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, drugstores
Approval Status
Approved by DGDA
Patent Status
Generic
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
More Medicines
Explore other medicines you might be interested in
