Desatrol
Generic Name
Desloratadine
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| desatrol 25 mg syrup | ৳ 25.00 | N/A |
Description
Overview of the medicine
Desatrol 2.5 mg/5 mL Syrup contains desloratadine, a non-drowsy antihistamine that provides relief from allergy symptoms such as sneezing, runny nose, itchy or watery eyes, and hives. The '25 mg' in the product name typically refers to the total desloratadine content in a standard bottle (e.g., 50 mL bottle).
Uses & Indications
Dosage
Adults
5 mg (10 mL of syrup) once daily.
Elderly
No specific dosage adjustment required, but use with caution in patients with renal or hepatic impairment.
Renal_impairment
For severe renal impairment, administer 5 mg every other day.
How to Take
Administer orally, with or without food. Use a measuring spoon or oral syringe to ensure accurate dosing, especially for children.
Mechanism of Action
Desloratadine is a long-acting tricyclic antihistamine with selective peripheral H1-receptor antagonist activity. It inhibits histamine release and other pro-inflammatory mediators from mast cells.
Pharmacokinetics
Onset
Onset of action within 1-2 hours.
Excretion
Excreted via urine and feces.
Half life
Approximately 27 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached approximately 3 hours after administration.
Metabolism
Extensively metabolized in the liver to 3-hydroxydesloratadine, an active metabolite.
Side Effects
Contraindications
- •Hypersensitivity to desloratadine, loratadine, or any component of the formulation.
- •Patients with severe kidney or liver disease (use with caution and dose adjustment)
Drug Interactions
Cimetidine
May increase desloratadine plasma levels.
Fluoxetine
May increase desloratadine plasma levels.
Azithromycin
May increase desloratadine plasma levels.
Erythromycin
May increase desloratadine plasma levels.
Ketoconazole
May increase desloratadine plasma levels.
Storage
Store at room temperature (below 30°C), protected from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, tachycardia, and headache. In the event of an overdose, symptomatic and supportive treatment should be initiated as clinically indicated. Desloratadine is not effectively removed by hemodialysis.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Desloratadine passes into breast milk, so caution should be exercised when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 to 36 months from manufacturing date when stored correctly.
Availability
Available in all licensed pharmacies
Approval Status
Approved by major regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available; original patent expired
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Global Brand Names
International brand names for this medicine
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