Deslor
Generic Name
Desloratadine
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| deslor 5 mg tablet | ৳ 5.00 | ৳ 50.00 |
Description
Overview of the medicine
Desloratadine is a non-drowsy antihistamine used to relieve allergy symptoms such as sneezing, runny nose, itchy or watery eyes, and skin rash (hives). It works by blocking a natural substance (histamine) that your body makes during an allergic reaction.
Uses & Indications
Dosage
Adults
5 mg once daily.
Elderly
No specific dose adjustment is generally required, but caution is advised in patients with renal or hepatic impairment.
Renal_impairment
For severe renal impairment (creatinine clearance < 30 mL/min), 5 mg every other day. Dosage adjustment may be required in moderate renal impairment.
How to Take
Desloratadine tablets may be taken with or without food. Swallow the tablet whole with water. Do not crush or chew.
Mechanism of Action
Desloratadine is a tricyclic antihistamine with selective peripheral H1-receptor antagonist activity. It prevents histamine from binding to H1 receptors, thereby alleviating allergic symptoms. It also has anti-inflammatory effects.
Pharmacokinetics
Onset
Within 30 minutes to 1 hour.
Excretion
Primarily excreted in urine and feces as metabolites.
Half life
Approximately 27 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations (Cmax) are achieved approximately 3 hours after dosing.
Metabolism
Extensively metabolized to 3-hydroxydesloratadine, an active metabolite, primarily via CYP2C8 and CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to desloratadine, loratadine, or any component of the formulation.
- History of allergic reactions to antihistamines.
Drug Interactions
Ketoconazole, Erythromycin, Azithromycin, Fluoxetine, Cimetidine
May increase plasma concentrations of desloratadine and its active metabolite, but generally without clinically significant adverse effects.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
In the event of an overdose, symptomatic and supportive treatment should be initiated. Desloratadine is not removed by hemodialysis.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if clearly needed and the potential benefits outweigh the potential risks to the fetus. Desloratadine is excreted in breast milk, so caution is advised in nursing mothers; consider discontinuing nursing or the drug.
Side Effects
Contraindications
- Hypersensitivity to desloratadine, loratadine, or any component of the formulation.
- History of allergic reactions to antihistamines.
Drug Interactions
Ketoconazole, Erythromycin, Azithromycin, Fluoxetine, Cimetidine
May increase plasma concentrations of desloratadine and its active metabolite, but generally without clinically significant adverse effects.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
In the event of an overdose, symptomatic and supportive treatment should be initiated. Desloratadine is not removed by hemodialysis.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if clearly needed and the potential benefits outweigh the potential risks to the fetus. Desloratadine is excreted in breast milk, so caution is advised in nursing mothers; consider discontinuing nursing or the drug.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from the manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved by major regulatory bodies globally
Patent Status
Generic available
Clinical Trials
Desloratadine has been extensively studied in numerous clinical trials for its efficacy and safety in the treatment of allergic rhinitis and chronic idiopathic urticaria across various patient populations, demonstrating consistent efficacy and a favorable safety profile.
Lab Monitoring
- No specific routine lab monitoring required for desloratadine use.
Doctor Notes
- Advise patients on the non-sedating nature of desloratadine, but caution about potential mild drowsiness in sensitive individuals.
- Emphasize the importance of adherence to the prescribed daily dose for optimal symptom control.
- Consider alternative antihistamines or additional therapies if symptoms are not adequately controlled.
Patient Guidelines
- Do not exceed the recommended dose.
- Inform your doctor or pharmacist about all medications, supplements, and herbal products you are taking.
- If you experience severe side effects, seek immediate medical attention.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
While desloratadine is generally non-sedating, some individuals may experience drowsiness. Exercise caution when driving or operating machinery until you know how this medicine affects you.
Lifestyle Advice
- Avoid known allergens that trigger your symptoms.
- Maintain good personal hygiene and keep your surroundings clean to reduce allergen exposure.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Deslor Brand
Other medicines available under the same brand name
