Desodin
Generic Name
Desodin 25 mg Syrup
Manufacturer
MediCo Pharma
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| desodin 25 mg syrup | ৳ 25.00 | N/A |
Description
Overview of the medicine
Desodin 25 mg Syrup is a non-sedating antihistamine used to relieve symptoms of various allergic conditions.
Uses & Indications
Dosage
Adults
25 mg (5 mL) once daily.
Elderly
No specific dosage adjustment is generally required, but caution is advised in patients with renal impairment.
Renal_impairment
For moderate to severe renal impairment (CrCl < 50 mL/min), consider 25 mg (5 mL) every other day. Consult a physician.
How to Take
Take orally, with or without food. Use a measuring spoon or cup for accurate dosing.
Mechanism of Action
Desodin selectively antagonizes peripheral H1-histamine receptors, thereby inhibiting the effects of histamine and reducing allergic symptoms.
Pharmacokinetics
Onset
Within 1-3 hours.
Excretion
Excreted in urine and feces as metabolites.
Half life
Approximately 27 hours, allowing for once-daily dosing.
Absorption
Rapidly absorbed after oral administration, with peak plasma concentrations reached within 1-3 hours.
Metabolism
Extensively metabolized in the liver, primarily via CYP3A4 and CYP2D6, into active and inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to desodin or any components of the syrup
- Severe renal impairment without dose adjustment
Drug Interactions
CNS depressants (e.g., alcohol, sedatives)
Although desodin is non-sedating, concomitant use may rarely potentiate central nervous system depression.
CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
May increase plasma concentrations of desodin. Use with caution.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, tachycardia, headache, and dry mouth. Management involves symptomatic and supportive care, gastric lavage, and activated charcoal.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Not recommended during breastfeeding as it may pass into breast milk.
Side Effects
Contraindications
- Hypersensitivity to desodin or any components of the syrup
- Severe renal impairment without dose adjustment
Drug Interactions
CNS depressants (e.g., alcohol, sedatives)
Although desodin is non-sedating, concomitant use may rarely potentiate central nervous system depression.
CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
May increase plasma concentrations of desodin. Use with caution.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, tachycardia, headache, and dry mouth. Management involves symptomatic and supportive care, gastric lavage, and activated charcoal.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Not recommended during breastfeeding as it may pass into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies, hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Patented
Clinical Trials
Multiple Phase III clinical trials have demonstrated the efficacy and safety of desodin in the treatment of allergic rhinitis and chronic idiopathic urticaria across diverse patient populations.
Lab Monitoring
- No routine lab monitoring is required.
Doctor Notes
- Educate patients on the non-sedating nature of desodin but advise caution for initial use.
- Counsel on adherence to prescribed dosage and the importance of avoiding known allergens.
- Monitor for symptom relief and any emergent adverse effects.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor.
- Do not exceed the recommended dose.
- Consult your doctor if symptoms do not improve or worsen.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Although Desodin is generally non-sedating, individuals may react differently. Exercise caution when driving or operating machinery until you know how this medicine affects you.
Lifestyle Advice
- Identify and avoid known allergens to help manage symptoms.
- Stay hydrated by drinking plenty of fluids.
- Maintain good hygiene to reduce exposure to irritants.
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Global Brand Names
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