Desodin
Generic Name
Desodin 5 mg Tablet
Manufacturer
Medicon Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| desodin 5 mg tablet | ৳ 4.00 | ৳ 40.00 |
Description
Overview of the medicine
Desodin 5 mg Tablet is an advanced, non-sedating antihistamine used for the relief of symptoms associated with allergic rhinitis and chronic idiopathic urticaria.
Uses & Indications
Dosage
Adults
1 tablet (5 mg) once daily.
Elderly
No dose adjustment is generally required, but caution is advised in patients with renal or hepatic impairment.
Renal_impairment
For patients with severe renal impairment (creatinine clearance < 30 mL/min), a reduced frequency of administration (e.g., 5 mg every other day) may be considered.
How to Take
Desodin 5 mg Tablet should be taken orally, with or without food. Swallow the tablet whole with water.
Mechanism of Action
Desodin selectively antagonizes peripheral H1-histamine receptors, thereby inhibiting the effects of histamine and alleviating allergic symptoms. It does not readily cross the blood-brain barrier, resulting in minimal to no sedation.
Pharmacokinetics
Onset
Onset of action typically occurs within 30-60 minutes.
Excretion
Excreted primarily in urine and feces as metabolites.
Half life
Approximately 27 hours.
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations are reached within 2-4 hours.
Metabolism
Extensively metabolized in the liver, primarily via hydroxylation.
Side Effects
Contraindications
- Hypersensitivity to desodin, desloratadine, loratadine, or any component of the formulation.
- Severe hepatic impairment.
Drug Interactions
Cimetidine
May increase plasma concentrations of desodin.
Erythromycin
May increase plasma concentrations of desodin.
Ketoconazole
May increase plasma concentrations of desodin.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be initiated. Desodin is not effectively removed by hemodialysis.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Not recommended during lactation as desodin is excreted in breast milk. Consult your doctor.
Side Effects
Contraindications
- Hypersensitivity to desodin, desloratadine, loratadine, or any component of the formulation.
- Severe hepatic impairment.
Drug Interactions
Cimetidine
May increase plasma concentrations of desodin.
Erythromycin
May increase plasma concentrations of desodin.
Ketoconazole
May increase plasma concentrations of desodin.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive treatment should be initiated. Desodin is not effectively removed by hemodialysis.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Not recommended during lactation as desodin is excreted in breast milk. Consult your doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patented
Clinical Trials
Desodin has undergone extensive Phase III clinical trials demonstrating its efficacy and safety in adult and adolescent patients with allergic rhinitis and chronic idiopathic urticaria.
Lab Monitoring
- No routine lab monitoring is generally required.
Doctor Notes
- Advise patients to take at the same time each day for consistent effect.
- Monitor for unusual or severe side effects, especially in patients with pre-existing conditions.
- Ensure patient understanding of non-sedating nature but advise caution with initial doses.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Desodin is generally non-sedating, but individual responses vary. Patients should assess their response to the drug before performing tasks requiring mental alertness, such as driving or operating machinery.
Lifestyle Advice
- Avoid known allergens to reduce the frequency and severity of allergic reactions.
- Maintain good hygiene to minimize exposure to dust mites and pet dander.
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