Desotem
Generic Name
Desotem 5 mg Tablet
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| desotem 5 mg tablet | ৳ 2.40 | ৳ 24.00 |
Description
Overview of the medicine
Desotem 5 mg Tablet is an antihistamine used to relieve symptoms of allergic conditions such as hay fever, allergic rhinitis, and chronic urticaria. It helps to reduce itching, sneezing, and runny nose.
Uses & Indications
Dosage
Adults
One 5 mg tablet once daily.
Elderly
No dose adjustment generally required, but caution is advised in patients with renal or hepatic impairment.
Renal_impairment
For severe renal impairment (creatinine clearance < 30 mL/min), initial dose of 5 mg every other day is recommended.
How to Take
Desotem 5 mg tablet can be taken with or without food. Swallow the tablet whole with a glass of water. Do not chew or crush.
Mechanism of Action
Desotem selectively antagonizes peripheral H1-receptors, preventing histamine from binding and exerting its effects, thereby reducing allergic symptoms. It does not readily cross the blood-brain barrier, leading to less sedation.
Pharmacokinetics
Onset
Within 30-60 minutes
Excretion
Mainly excreted via urine and feces as metabolites.
Half life
Approximately 20-24 hours
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations reached within 1-2 hours.
Metabolism
Extensively metabolized in the liver to active and inactive metabolites, primarily via CYP3A4.
Side Effects
Contraindications
- Hypersensitivity to Desotem or any of its excipients or to loratadine.
- Severe hepatic impairment.
Drug Interactions
Alcohol
No potentiation of alcohol-induced impairment, but concurrent use should be approached with caution.
Ketoconazole, Erythromycin, Azithromycin, Cimetidine
May increase plasma concentration of Desotem, but without clinically significant effects. Caution advised.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, tachycardia, and headache. Treatment is symptomatic and supportive. Gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy Category C. Use only if clearly needed. Excreted in breast milk, so caution advised during lactation.
Side Effects
Contraindications
- Hypersensitivity to Desotem or any of its excipients or to loratadine.
- Severe hepatic impairment.
Drug Interactions
Alcohol
No potentiation of alcohol-induced impairment, but concurrent use should be approached with caution.
Ketoconazole, Erythromycin, Azithromycin, Cimetidine
May increase plasma concentration of Desotem, but without clinically significant effects. Caution advised.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, tachycardia, and headache. Treatment is symptomatic and supportive. Gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy Category C. Use only if clearly needed. Excreted in breast milk, so caution advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patent pending
Clinical Trials
Extensive clinical trials have demonstrated Desotem's efficacy and safety in treating allergic rhinitis and chronic urticaria, showing rapid onset of action and sustained symptom relief.
Lab Monitoring
- No routine lab monitoring required for healthy individuals. Liver function tests may be considered in patients with hepatic impairment.
Doctor Notes
- Advise patients to take at the same time each day for best results.
- Monitor for unusual drowsiness, especially in elderly patients or those with renal impairment.
- Patients should be counselled on allergen avoidance strategies.
Patient Guidelines
- Take Desotem 5 mg tablet exactly as prescribed by your doctor.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Desotem is generally non-sedating, but individuals sensitive to the drug may experience drowsiness. Exercise caution when driving or operating machinery until you know how Desotem affects you.
Lifestyle Advice
- Avoid known allergens to reduce symptoms.
- Maintain good hydration.
- Get adequate rest.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Desotem Brand
Other medicines available under the same brand name
