Dexcor
Generic Name
Dexamethasone
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| dexcor 5 mg injection | ৳ 22.00 | N/A |
Description
Overview of the medicine
Dexamethasone is a potent synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. It is used to treat various conditions, including allergic disorders, inflammatory conditions, autoimmune diseases, and certain cancers.
Uses & Indications
Dosage
Adults
Dosage varies widely based on condition. Typically 0.5-20 mg daily via IM/IV, or as prescribed by physician.
Elderly
Lower doses may be required; caution needed due to increased susceptibility to side effects.
Renal_impairment
No specific dose adjustment typically needed, but monitor closely.
How to Take
Administer intramuscularly or intravenously, slowly over 1-4 minutes. Do not inject subcutaneously.
Mechanism of Action
Dexamethasone binds to glucocorticoid receptors, inhibiting the release of inflammatory mediators and suppressing immune responses.
Pharmacokinetics
Onset
Rapid (within minutes to hours depending on route).
Excretion
Primarily renal.
Half life
Plasma half-life 3-4.5 hours; biological half-life 36-72 hours.
Absorption
Rapidly and completely absorbed after IM/IV injection.
Metabolism
Primarily hepatic, mainly via CYP3A4.
Side Effects
Contraindications
- •Systemic fungal infections
- •Hypersensitivity to dexamethasone or any component
- •Live virus vaccines during corticosteroid therapy
Drug Interactions
NSAIDs
Increased risk of gastrointestinal ulcers.
Warfarin
May alter anticoagulant effects; monitor INR.
Phenytoin
May decrease dexamethasone levels.
Storage
Store below 30°C, protected from light. Do not freeze.
Overdose
Symptoms include exaggerated side effects (e.g., fluid retention, hypertension, hyperglycemia). Management is supportive and symptomatic.
Pregnancy & Lactation
Use with caution; weighs potential benefits against risks. Dexamethasone crosses the placenta and is excreted in breast milk. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Hospitals, Clinics, Pharmacies
Approval Status
Approved by regulatory authorities
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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