elfexo
Generic Name
fexofenadine hydrochloride
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| elfexo 120 mg tablet | ৳ 7.00 | N/A |
Description
Overview of the medicine
Fexofenadine is a non-sedating antihistamine used to relieve symptoms of seasonal allergic rhinitis and chronic idiopathic urticaria.
Uses & Indications
Dosage
Adults
For Seasonal Allergic Rhinitis: 120 mg once daily or 60 mg twice daily. For Chronic Idiopathic Urticaria: 180 mg once daily.
Elderly
No specific dose adjustment generally needed, but monitor renal function.
Renal_impairment
For severe renal impairment (CrCl < 10 mL/min), 60 mg once daily is recommended.
How to Take
Orally, with water, preferably before a meal. Do not take with fruit juice.
Mechanism of Action
Fexofenadine is a selective peripheral H1-receptor antagonist. It inhibits histamine release and reduces allergic symptoms without causing significant drowsiness.
Pharmacokinetics
Onset
1 hour
Excretion
Primarily through feces (80%), some in urine (12%).
Half life
11-15 hours
Absorption
Rapidly absorbed after oral administration. Peak plasma concentrations in 2-3 hours.
Metabolism
Minimally metabolized (less than 5%).
Side Effects
Contraindications
- Known hypersensitivity to fexofenadine or any component of the formulation.
Drug Interactions
Erythromycin, Ketoconazole
May increase plasma levels of fexofenadine, but generally not clinically significant.
Aluminum and Magnesium containing Antacids
Reduce fexofenadine absorption. Separate administration by 2 hours.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include dizziness, drowsiness, dry mouth. Treatment is symptomatic and supportive. Gastric lavage and activated charcoal may be considered. Hemodialysis is ineffective.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies the potential risk to the fetus. Excreted in breast milk; use with caution in breastfeeding mothers.
Side Effects
Contraindications
- Known hypersensitivity to fexofenadine or any component of the formulation.
Drug Interactions
Erythromycin, Ketoconazole
May increase plasma levels of fexofenadine, but generally not clinically significant.
Aluminum and Magnesium containing Antacids
Reduce fexofenadine absorption. Separate administration by 2 hours.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include dizziness, drowsiness, dry mouth. Treatment is symptomatic and supportive. Gastric lavage and activated charcoal may be considered. Hemodialysis is ineffective.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies the potential risk to the fetus. Excreted in breast milk; use with caution in breastfeeding mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Expired
Clinical Trials
Extensive clinical trials have demonstrated fexofenadine's efficacy and safety in treating allergic rhinitis and chronic urticaria.
Lab Monitoring
- Generally not required.
Doctor Notes
- Advise patients to avoid concurrent use of antacids containing aluminum or magnesium within 2 hours of fexofenadine.
- Counsel patients on avoiding fruit juices due to potential reduction in efficacy.
Patient Guidelines
- Take as directed by your doctor.
- Do not exceed the recommended dose.
- Avoid taking with fruit juices.
- Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
- Store in a cool, dry place away from children.
Missed Dose Advice
Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Driving Precautions
Although non-sedating, individual responses vary. Exercise caution when driving or operating machinery until you know how the medicine affects you.
Lifestyle Advice
- Avoid known allergens to minimize symptoms.
- Maintain good hygiene to reduce exposure to allergens.
- Ensure adequate hydration.
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