Elfexo
Generic Name
Fexofenadine Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| elfexo 30 mg suspension | ৳ 50.00 | N/A |
Description
Overview of the medicine
Elfexo 30 mg suspension is an antihistamine medication used to relieve symptoms of seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives) in children. It works by blocking histamine, a natural substance that the body produces during an allergic reaction, thereby reducing symptoms like sneezing, runny nose, itchy eyes, and skin rashes.
Uses & Indications
Dosage
Renal_impairment
For children 2 to 11 years with impaired renal function, the recommended starting dose is 30 mg once daily. For children 6 months to 2 years with impaired renal function, the recommended starting dose is 15 mg once daily.
Children_2_11_years
For Seasonal Allergic Rhinitis: 30 mg (5 mL) orally twice daily. For Chronic Idiopathic Urticaria: 30 mg (5 mL) orally twice daily.
Children_6_months_2_years
For Chronic Idiopathic Urticaria: 15 mg (2.5 mL) orally twice daily.
How to Take
Administer orally using the provided measuring device. Can be taken with or without food. Avoid taking with fruit juices (grapefruit, orange, apple) as they may reduce the absorption of fexofenadine.
Mechanism of Action
Fexofenadine is a selective peripheral H1-receptor antagonist. It effectively blocks the histamine H1 receptors on cells, preventing histamine from binding and causing allergic symptoms. It has minimal to no central nervous system penetration, resulting in a non-sedating profile.
Pharmacokinetics
Onset
Onset of action within 1 hour.
Excretion
Approximately 80% excreted unchanged in feces and 11% in urine.
Half life
Plasma elimination half-life of approximately 11-15 hours.
Absorption
Rapidly absorbed after oral administration; peak plasma concentrations reached in approximately 1-3 hours. Absorption is reduced by fruit juices.
Metabolism
Undergoes negligible hepatic metabolism (less than 5% of the dose).
Side Effects
Contraindications
- •Known hypersensitivity to fexofenadine or any of its excipients.
Drug Interactions
Erythromycin or Ketoconazole
Concomitant use with erythromycin or ketoconazole may increase plasma levels of fexofenadine. Monitor for increased side effects.
Antacids (aluminum and magnesium containing)
Co-administration may reduce the bioavailability of fexofenadine. Separate administration by at least 2 hours.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Symptoms of overdose include dizziness, drowsiness, and dry mouth. In case of overdose, initiate symptomatic and supportive treatment. Hemodialysis does not effectively remove fexofenadine from blood.
Pregnancy & Lactation
Pregnancy Category C. Use only if the potential benefit justifies the potential risk to the fetus. Fexofenadine is excreted into human breast milk; exercise caution when administering to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date when stored unopened.
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA and internationally
Patent Status
Generic available, original patent expired
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