Emiprox DS
Generic Name
Esomeprazole
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| emiprox ds 80 mg suspension | ৳ 170.00 | N/A |
Description
Overview of the medicine
Emiprox DS contains Esomeprazole, a proton pump inhibitor used to treat acid-related disorders like GERD, erosive esophagitis, and stomach ulcers.
Uses & Indications
Dosage
Adults
For GERD: 20-40 mg once daily for 4-8 weeks. For Zollinger-Ellison Syndrome: 40 mg twice daily, adjusted as per patient response.
Elderly
No dose adjustment generally required, but caution is advised in patients with severe hepatic impairment.
Renal_impairment
No dose adjustment is needed for mild to moderate renal impairment. For severe impairment, caution is advised.
How to Take
Take orally, at least one hour before a meal, preferably in the morning. Swallow the tablet whole; do not chew, crush, or break it.
Mechanism of Action
Irreversibly blocks the H+/K+-ATPase (proton pump) in gastric parietal cells, thereby reducing gastric acid secretion.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Mainly excreted via urine (approximately 80%) and feces (approximately 20%) as metabolites.
Half life
Approximately 1-1.5 hours
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations typically occur within 1-2 hours.
Metabolism
Extensively metabolized in the liver by the cytochrome P450 enzyme system, primarily CYP2C19 and CYP3A4.
Side Effects
Contraindications
- Known hypersensitivity to Esomeprazole, substituted benzimidazoles, or any component of the formulation.
- Concomitant use with nelfinavir.
Drug Interactions
Digoxin
Increased bioavailability of digoxin.
Diazepam
Increased plasma concentrations of diazepam.
Warfarin
Increased INR and bleeding risk due to altered metabolism.
Clopidogrel
Reduced antiplatelet effect of clopidogrel.
Storage
Store in a cool, dry place, below 30°C (86°F). Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, tachycardia, nausea, headache, and abdominal pain. Treatment is symptomatic and supportive. There is no specific antidote.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Esomeprazole is excreted in human breast milk; therefore, caution is advised when administered to a nursing woman.
Side Effects
Contraindications
- Known hypersensitivity to Esomeprazole, substituted benzimidazoles, or any component of the formulation.
- Concomitant use with nelfinavir.
Drug Interactions
Digoxin
Increased bioavailability of digoxin.
Diazepam
Increased plasma concentrations of diazepam.
Warfarin
Increased INR and bleeding risk due to altered metabolism.
Clopidogrel
Reduced antiplatelet effect of clopidogrel.
Storage
Store in a cool, dry place, below 30°C (86°F). Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, tachycardia, nausea, headache, and abdominal pain. Treatment is symptomatic and supportive. There is no specific antidote.
Pregnancy & Lactation
Pregnancy Category C. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Esomeprazole is excreted in human breast milk; therefore, caution is advised when administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from the date of manufacture.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of Esomeprazole for its approved indications, leading to its widespread use in gastroenterology.
Lab Monitoring
- Magnesium levels (for long-term use, especially with diuretics)
- Liver function tests (if liver impairment is suspected or develops)
- Vitamin B12 levels (for prolonged use due to potential malabsorption)
Doctor Notes
- Prescribe the lowest effective dose for the shortest duration consistent with the patient's condition.
- Monitor patients on long-term therapy for potential adverse effects, including hypomagnesemia and bone fractures.
- Consider the patient's CYP2C19 metabolic status, especially if treatment response is suboptimal.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor.
- Do not stop treatment early, even if your symptoms improve, unless advised by your doctor.
- Report any severe or persistent side effects to your doctor immediately.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Emiprox DS may cause dizziness or visual disturbances in some patients. Use caution when driving or operating machinery until you know how this medication affects you.
Lifestyle Advice
- Avoid trigger foods such as spicy, fatty, or acidic foods and beverages.
- Eat smaller, more frequent meals instead of large ones.
- Elevate the head of your bed if you suffer from GERD to reduce nighttime reflux.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.