Emlino
Generic Name
Empagliflozin
Manufacturer
Acme Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| emlino 25 mg tablet | ৳ 40.00 | ৳ 400.00 |
Description
Overview of the medicine
Empagliflozin is an oral antidiabetic drug used to treat type 2 diabetes mellitus, heart failure, and chronic kidney disease.
Uses & Indications
Dosage
Adults
Initial dose 10 mg once daily, may be increased to 25 mg once daily.
Elderly
No dose adjustment generally required based on age alone, but renal function should be considered.
Renal_impairment
Not recommended for initiation if eGFR < 20 mL/min/1.73m², dosage adjustment may be needed for specific eGFR ranges.
How to Take
Take orally once daily in the morning, with or without food.
Mechanism of Action
Empagliflozin inhibits the SGLT2 transporter in the kidneys, reducing glucose reabsorption and increasing glucose excretion in the urine, thereby lowering blood glucose levels.
Pharmacokinetics
Onset
Glucose-lowering effect typically observed within 24 hours.
Excretion
Approximately 50% renally excreted and 50% fecally excreted.
Half life
Approximately 10-13 hours.
Absorption
Rapidly absorbed after oral administration, peak plasma concentrations typically reached 1.5 hours post-dose.
Metabolism
Primarily metabolized by glucuronidation by UGT1A8, UGT1A3, UGT1A9, and UGT2B7.
Side Effects
Contraindications
- •Hypersensitivity to empagliflozin or any component of the formulation
- •Severe renal impairment, end-stage renal disease, or dialysis
Drug Interactions
Diuretics
May increase risk of dehydration and hypotension.
Insulin and Insulin Secretagogues
May increase risk of hypoglycemia.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Management involves symptomatic treatment and monitoring of glucose and electrolyte levels.
Pregnancy & Lactation
Not recommended during pregnancy, especially in the second and third trimesters. Avoid during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies, hospitals
Approval Status
FDA approved
Patent Status
Patented
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Global Brand Names
International brand names for this medicine
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