Evit-C
Generic Name
evit-c
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| evit c 250 mg chewable tablet | ৳ 1.90 | ৳ 19.00 |
Description
Overview of the medicine
Evit-C is a combination of Vitamin E (Tocopherol) and Vitamin C (Ascorbic Acid), both potent antioxidants essential for overall health, immune function, and skin integrity. It helps protect cells from oxidative damage caused by free radicals.
Uses & Indications
Dosage
Adults
Usually 1-2 capsules daily, or as directed by a physician.
Elderly
Same as adult dose, or as advised by a physician, with consideration for renal function.
Renal_impairment
Caution is advised for high doses of Vitamin C in patients with severe renal impairment due to risk of oxalate stone formation. Consult a physician.
How to Take
Oral, preferably with or after meals to enhance absorption and reduce gastrointestinal upset.
Mechanism of Action
Both Vitamin E and Vitamin C act as antioxidants. Vitamin E is a fat-soluble antioxidant that protects cell membranes from oxidative damage. Vitamin C is a water-soluble antioxidant that neutralizes free radicals in aqueous compartments and regenerates oxidized Vitamin E, enhancing its antioxidant capacity.
Pharmacokinetics
Onset
Gradual, benefits build up with consistent use.
Excretion
Primarily renal excretion for Vitamin C. Vitamin E is primarily excreted via bile and feces.
Half life
Vitamin E's half-life is several days, Vitamin C's is about 10-20 days depending on dose and tissue saturation.
Absorption
Well absorbed orally, Vitamin E absorption requires bile salts, Vitamin C is actively absorbed in the small intestine.
Metabolism
Vitamin E is metabolized in the liver. Vitamin C is primarily excreted unchanged or as oxalate in urine, with some metabolism to dehydroascorbic acid.
Side Effects
Contraindications
- •Hypersensitivity to any component of Evit-C
- •High doses of Vitamin C are contraindicated in patients with hyperoxaluria, glucose-6-phosphate dehydrogenase deficiency, and hemochromatosis.
Drug Interactions
Iron supplements
Vitamin C can enhance iron absorption, which might be an issue for individuals with hemochromatosis.
Chemotherapy drugs
High doses of antioxidants like Vitamin C may interfere with the efficacy of some chemotherapy agents, consult oncologist.
Anticoagulants (e.g., Warfarin)
High doses of Vitamin E may increase the risk of bleeding.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Acute overdose is rare and generally well-tolerated. High doses of Vitamin C may cause gastrointestinal upset, diarrhea, and an increased risk of kidney stones in susceptible individuals. High doses of Vitamin E are generally considered safe but may rarely cause mild symptoms like nausea or fatigue. Management is supportive.
Pregnancy & Lactation
Generally considered safe at recommended daily allowances. However, high doses should be avoided during pregnancy and lactation unless specifically advised by a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 to 36 months from manufacturing date.
Availability
All pharmacies nationwide
Approval Status
Approved
Patent Status
Generic
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