Exalin
Generic Name
Salbutamol (Albuterol)
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| exalin 10 mg tablet | ৳ 12.00 | ৳ 168.00 |
Description
Overview of the medicine
Exalin is a bronchodilator containing Salbutamol, used to relieve symptoms of asthma and chronic obstructive pulmonary disease (COPD) such as coughing, wheezing, and shortness of breath. It works by relaxing the muscles in the airways to improve breathing.
Uses & Indications
Dosage
Adults
Oral: 2-4 mg three to four times daily. Inhalation: 1-2 puffs (100-200 mcg) as needed, up to 4 times a day.
Elderly
May require lower doses due to potential increased sensitivity.
Renal_impairment
No specific dosage adjustment needed, but caution advised.
How to Take
Tablets should be taken with water. Inhalers should be used according to the manufacturer's instructions, ensuring proper technique.
Mechanism of Action
Salbutamol is a selective beta-2 adrenergic receptor agonist. It stimulates beta-2 receptors in the lungs, leading to relaxation of bronchial smooth muscle and bronchodilation. It also inhibits the release of mast cell mediators, further reducing bronchospasm.
Pharmacokinetics
Onset
5-15 minutes (inhalation), 30 minutes (oral)
Excretion
Primarily excreted in urine as unchanged drug and its metabolite.
Half life
2.7 to 5 hours (oral), 3.8 hours (inhalation)
Absorption
Rapidly absorbed from the gastrointestinal tract and lungs.
Metabolism
Undergoes hepatic metabolism to an inactive sulfate conjugate.
Side Effects
Contraindications
- •Hypersensitivity to salbutamol or any component of the formulation
- •Thyrotoxicosis (relative contraindication)
Drug Interactions
Diuretics
May cause hypokalemia.
Beta-blockers (e.g., Propranolol)
Can block the bronchodilator effect of salbutamol.
Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants (TCAs)
May potentiate cardiovascular effects.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms include tachycardia, tremors, hypokalemia, and metabolic acidosis. Treatment is supportive, including discontinuing the drug, monitoring vital signs and potassium levels.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit outweighs the potential risk to the fetus. Excreted in breast milk, use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months, varies by formulation and manufacturer
Availability
Available in all pharmacies and hospitals in Bangladesh
Approval Status
Approved by DGDA/FDA
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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