Favozyth
Generic Name
Favozyth-500-mg-tablet
Manufacturer
MediCare Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| favozyth 500 mg tablet | ৳ 50.00 | ৳ 300.00 |
Description
Overview of the medicine
Favozyth 500 mg Tablet is a broad-spectrum macrolide antibiotic used to treat various bacterial infections, including respiratory tract infections, skin and soft tissue infections, and certain sexually transmitted diseases.
Uses & Indications
Dosage
Adults
500 mg once daily for 3 days, or 500 mg as a single dose on day 1, followed by 250 mg once daily on days 2-5.
Elderly
No dosage adjustment required.
Renal_impairment
No dosage adjustment required for mild to moderate renal impairment; caution advised in severe impairment.
How to Take
Favozyth tablets can be taken with or without food. It is important to complete the full course of treatment as prescribed by your doctor.
Mechanism of Action
Favozyth inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of susceptible microorganisms, thereby interfering with the translocation of peptides.
Pharmacokinetics
Onset
Within 2-3 hours.
Excretion
Mainly excreted unchanged in bile; a smaller portion is excreted in urine.
Half life
Approximately 48-68 hours, allowing for once-daily dosing.
Absorption
Rapidly absorbed after oral administration, bioavailability is approximately 37%.
Metabolism
Primarily hepatic, undergoing N-demethylation.
Side Effects
Contraindications
- Hypersensitivity to favozyth, erythromycin, or any macrolide antibiotic.
- History of cholestatic jaundice/hepatic dysfunction associated with prior favozyth use.
Drug Interactions
Digoxin
Increased plasma levels of digoxin; monitor digoxin levels.
Antacids
Concurrent administration with antacids may reduce favozyth peak plasma concentrations. Administer favozyth at least 2 hours before or 4 hours after antacids.
Warfarin
Increased anticoagulant effect when favozyth is co-administered with warfarin; monitor prothrombin time.
Cyclosporine
Increased plasma levels of cyclosporine; monitor cyclosporine levels.
QT-prolonging drugs
Avoid co-administration with other drugs known to prolong the QT interval (e.g., Class IA and III antiarrhythmics, certain antipsychotics).
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe nausea, vomiting, diarrhea, and reversible hearing loss. Management involves symptomatic and supportive treatment, including gastric lavage and general supportive measures.
Pregnancy & Lactation
Pregnancy Category B. Favozyth should be used during pregnancy only if clearly needed. Excreted in breast milk; caution should be exercised when Favozyth is administered to a nursing woman.
Side Effects
Contraindications
- Hypersensitivity to favozyth, erythromycin, or any macrolide antibiotic.
- History of cholestatic jaundice/hepatic dysfunction associated with prior favozyth use.
Drug Interactions
Digoxin
Increased plasma levels of digoxin; monitor digoxin levels.
Antacids
Concurrent administration with antacids may reduce favozyth peak plasma concentrations. Administer favozyth at least 2 hours before or 4 hours after antacids.
Warfarin
Increased anticoagulant effect when favozyth is co-administered with warfarin; monitor prothrombin time.
Cyclosporine
Increased plasma levels of cyclosporine; monitor cyclosporine levels.
QT-prolonging drugs
Avoid co-administration with other drugs known to prolong the QT interval (e.g., Class IA and III antiarrhythmics, certain antipsychotics).
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include severe nausea, vomiting, diarrhea, and reversible hearing loss. Management involves symptomatic and supportive treatment, including gastric lavage and general supportive measures.
Pregnancy & Lactation
Pregnancy Category B. Favozyth should be used during pregnancy only if clearly needed. Excreted in breast milk; caution should be exercised when Favozyth is administered to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patent expired
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated Favozyth's efficacy and safety in treating a wide range of bacterial infections.
Lab Monitoring
- Liver function tests (for prolonged therapy or in patients with pre-existing hepatic impairment)
- Renal function tests (if renal impairment is severe)
- ECG monitoring (in patients at risk of QT prolongation)
Doctor Notes
- Emphasize patient compliance to complete the entire course of therapy to minimize resistance development.
- Counsel patients on potential QT prolongation risks, especially if co-administering with other interacting drugs.
- Monitor liver function in patients with pre-existing hepatic impairment.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor, even if you feel better.
- Do not stop taking the medicine early, as this can lead to antibiotic resistance.
- Inform your doctor about all other medications you are taking.
- Seek immediate medical attention if you experience severe allergic reactions.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.
Driving Precautions
Favozyth may cause dizziness in some individuals. If you experience dizziness, avoid driving or operating heavy machinery.
Lifestyle Advice
- Maintain good hydration while on antibiotic therapy.
- Avoid alcohol consumption, especially if you experience gastrointestinal side effects.
- Practice good hygiene to prevent the spread of infection.
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Global Brand Names
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