Feminor
Generic Name
Norethisterone
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| feminor 5 mg tablet | ৳ 6.84 | ৳ 68.40 |
Description
Overview of the medicine
Feminor is a synthetic progestogen used in various gynecological conditions including menstrual disorders, endometriosis, and as a component of hormone replacement therapy.
Uses & Indications
Dosage
Adults
For menstrual disorders: 5 mg 2-3 times daily from day 5 to day 25 of the cycle. For endometriosis: 5-10 mg daily continuously for 6-9 months.
Elderly
Dosage adjustments generally not required, but caution with liver/kidney impairment.
Renal_impairment
Use with caution; close monitoring recommended.
How to Take
Oral administration with water, with or without food.
Mechanism of Action
Norethisterone acts by mimicking the effects of natural progesterone, primarily on the endometrium, inhibiting the release of gonadotropins (LH and FSH) and preventing ovulation. It also causes decidualization of the endometrium, making it unsuitable for implantation.
Pharmacokinetics
Onset
Effects typically begin within a few hours.
Excretion
Mainly excreted in urine (50-70%) and feces (20-40%) as metabolites.
Half life
Approximately 5-12 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within 1-2 hours.
Metabolism
Extensively metabolized in the liver, primarily by reduction and conjugation.
Side Effects
Contraindications
- Pregnancy or suspected pregnancy
- Undiagnosed vaginal bleeding
- Severe liver disease
- History of thromboembolic disorders
- Hormone-sensitive cancers (e.g., breast cancer)
Drug Interactions
Phenytoin
May reduce efficacy of norethisterone.
Rifampicin
May reduce efficacy of norethisterone.
Anticoagulants
May alter anticoagulant effects.
St. John's Wort
May reduce efficacy of norethisterone.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, breast tenderness, vaginal bleeding. Treatment is symptomatic and supportive; no specific antidote.
Pregnancy & Lactation
Contraindicated during pregnancy. Use with caution during lactation as small amounts may pass into breast milk.
Side Effects
Contraindications
- Pregnancy or suspected pregnancy
- Undiagnosed vaginal bleeding
- Severe liver disease
- History of thromboembolic disorders
- Hormone-sensitive cancers (e.g., breast cancer)
Drug Interactions
Phenytoin
May reduce efficacy of norethisterone.
Rifampicin
May reduce efficacy of norethisterone.
Anticoagulants
May alter anticoagulant effects.
St. John's Wort
May reduce efficacy of norethisterone.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include nausea, vomiting, breast tenderness, vaginal bleeding. Treatment is symptomatic and supportive; no specific antidote.
Pregnancy & Lactation
Contraindicated during pregnancy. Use with caution during lactation as small amounts may pass into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensively studied in clinical trials for its indicated uses, confirming efficacy and safety profile.
Lab Monitoring
- Regular blood pressure checks
- Liver function tests (for long-term use)
- Pelvic examination and Pap test annually
Doctor Notes
- Emphasize proper patient selection and regular follow-up.
- Counsel patients on potential side effects and when to seek medical attention.
- Consider lowest effective dose for shortest duration.
Patient Guidelines
- Take medicine at the same time each day.
- Do not stop taking the medicine without consulting your doctor.
- Report any unusual bleeding or severe side effects immediately.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.
Driving Precautions
Generally no impact, but if dizziness occurs, avoid driving.
Lifestyle Advice
- Maintain a healthy diet and regular exercise.
- Avoid smoking, especially if over 35 years old.
- Discuss any pre-existing medical conditions with your doctor.
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Global Brand Names
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