Feriz TR
Generic Name
Ferrous Fumarate + Folic Acid + Zinc Sulfate Monohydrate
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| feriz tr 150 mg capsule | ৳ 2.90 | N/A |
Description
Overview of the medicine
Feriz TR is an anti-anaemic preparation containing ferrous fumarate, folic acid, and zinc sulfate, designed to treat and prevent iron deficiency anemia and megaloblastic anemia due to folate deficiency. The 'TR' indicates a sustained-release formulation.
Uses & Indications
Dosage
Adults
One capsule daily, or as directed by a physician.
Elderly
No specific dose adjustment required, follow adult dosage.
Renal_impairment
Use with caution in severe renal impairment. Consult physician.
How to Take
Take orally, preferably after meals to minimize gastrointestinal upset. Swallow the capsule whole, do not chew or crush.
Mechanism of Action
Ferrous Fumarate provides elemental iron, which is essential for hemoglobin synthesis and oxygen transport. Folic acid is vital for erythropoiesis and nucleoprotein synthesis. Zinc is an essential trace element involved in numerous enzymatic reactions and immune function.
Pharmacokinetics
Onset
Anaemia correction takes several weeks to months.
Excretion
Iron is mainly excreted through feces. Folic acid and its metabolites are excreted in urine and feces. Zinc is primarily excreted via feces.
Half life
Iron half-life depends on body needs. Folic acid half-life is about 3-6 hours. Zinc half-life varies.
Absorption
Iron is primarily absorbed in the duodenum and proximal jejunum. Folic acid is rapidly absorbed from the gastrointestinal tract. Zinc is absorbed primarily from the small intestine.
Metabolism
Iron is incorporated into hemoglobin and myoglobin. Folic acid is metabolized in the liver to active forms. Zinc is not extensively metabolized.
Side Effects
Contraindications
- Hypersensitivity to any component
- Hemochromatosis and other iron overload syndromes
- Repeated blood transfusions
- Pernicious anemia (without vitamin B12 therapy)
Drug Interactions
Antacids
Can reduce iron absorption. Separate administration by several hours.
Methotrexate
Folic acid may interfere with the action of methotrexate.
Levothyroxine
Iron may reduce absorption of levothyroxine. Separate administration by 4 hours.
Tetracyclines & Quinolones
Iron can decrease the absorption of these antibiotics. Take iron 2 hours before or 4 hours after.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture.
Overdose
Symptoms include severe gastrointestinal upset, metabolic acidosis, cardiovascular collapse. Seek immediate medical attention. Treatment involves gastric lavage, chelation therapy (e.g., deferoxamine) for iron, and supportive care.
Pregnancy & Lactation
Essential during pregnancy and lactation to prevent and treat deficiencies. Consult a physician for appropriate dosage.
Side Effects
Contraindications
- Hypersensitivity to any component
- Hemochromatosis and other iron overload syndromes
- Repeated blood transfusions
- Pernicious anemia (without vitamin B12 therapy)
Drug Interactions
Antacids
Can reduce iron absorption. Separate administration by several hours.
Methotrexate
Folic acid may interfere with the action of methotrexate.
Levothyroxine
Iron may reduce absorption of levothyroxine. Separate administration by 4 hours.
Tetracyclines & Quinolones
Iron can decrease the absorption of these antibiotics. Take iron 2 hours before or 4 hours after.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture.
Overdose
Symptoms include severe gastrointestinal upset, metabolic acidosis, cardiovascular collapse. Seek immediate medical attention. Treatment involves gastric lavage, chelation therapy (e.g., deferoxamine) for iron, and supportive care.
Pregnancy & Lactation
Essential during pregnancy and lactation to prevent and treat deficiencies. Consult a physician for appropriate dosage.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, drugstores
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials support the efficacy of iron and folic acid in treating and preventing anemias. Specific trials for Feriz TR would be conducted by the manufacturer.
Lab Monitoring
- Complete Blood Count (CBC)
- Serum ferritin levels
- Iron studies (serum iron, TIBC, transferrin saturation)
- Folate levels
Doctor Notes
- Advise patients about potential dark stools.
- Emphasize taking with food to reduce GI side effects.
- Counsel on drug-food interactions.
Patient Guidelines
- Take as directed by your doctor.
- Do not exceed the recommended dose.
- Store out of reach of children.
- Report any severe side effects to your doctor.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Generally, this medicine does not impair driving ability. However, if you experience dizziness or fatigue, avoid driving.
Lifestyle Advice
- Maintain a balanced diet rich in iron (e.g., red meat, leafy greens, fortified cereals).
- Ensure adequate vitamin C intake to aid iron absorption.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.