Ferroglobin
Generic Name
Iron, Folic Acid and Vitamin B12
Manufacturer
Vitabiotics (UK)
Country
United Kingdom
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ferroglobin 200 mg syrup | ৳ 40.25 | N/A |
Description
Overview of the medicine
Ferroglobin is an iron supplement, often combined with folic acid and vitamin B12, designed to help maintain healthy red blood cell formation and energy levels. It is used to prevent and treat iron deficiency anemia and other nutritional deficiencies.
Uses & Indications
Dosage
Adults
1 capsule/tablet or 10 ml syrup once daily, or as directed by a physician.
Elderly
Same as adult dosage, or as advised by a physician.
Renal_impairment
Use with caution. Dosage adjustment may be required in severe cases, consult a physician.
How to Take
Should be taken with or after meals to minimize gastrointestinal upset. Avoid taking with tea, coffee, or calcium-rich foods as they can inhibit iron absorption.
Mechanism of Action
Iron is essential for hemoglobin synthesis, which transports oxygen. Folic acid and Vitamin B12 are crucial for DNA synthesis and red blood cell maturation. This combination ensures optimal erythropoiesis.
Pharmacokinetics
Onset
Symptomatic improvement may be seen within days; hemoglobin levels increase over several weeks.
Excretion
Iron is minimally excreted. Folic acid and B12 are excreted mainly via urine.
Half life
Iron: Variable, depends on body stores. Folic acid: 1 hour. Vitamin B12: 6 days.
Absorption
Iron is absorbed primarily in the duodenum and upper jejunum. Folic acid and B12 are absorbed in the small intestine.
Metabolism
Iron is stored bound to ferritin. Folic acid and B12 are metabolized in the liver.
Side Effects
Contraindications
- Hemochromatosis
- Hemosiderosis
- Known hypersensitivity to any component
- Non-iron deficiency anemia (e.g., hemolytic anemia)
Drug Interactions
Antacids
Reduce iron absorption. Take iron 2 hours before or 4 hours after antacids.
Levothyroxine
May reduce levothyroxine efficacy. Administer iron several hours apart.
Tetracyclines & Quinolones
Reduce absorption of both iron and antibiotics. Take iron 2 hours before or 4-6 hours after.
Storage
Store below 30°C in a dry place, protected from light. Keep out of reach of children.
Overdose
Symptoms include severe gastrointestinal upset, metabolic acidosis, cardiovascular collapse. Seek immediate medical attention. Treatment involves gastric lavage, chelation therapy (e.g., deferoxamine) if severe.
Pregnancy & Lactation
Considered safe and often recommended for iron and vitamin deficiencies during pregnancy and lactation. Consult a physician.
Side Effects
Contraindications
- Hemochromatosis
- Hemosiderosis
- Known hypersensitivity to any component
- Non-iron deficiency anemia (e.g., hemolytic anemia)
Drug Interactions
Antacids
Reduce iron absorption. Take iron 2 hours before or 4 hours after antacids.
Levothyroxine
May reduce levothyroxine efficacy. Administer iron several hours apart.
Tetracyclines & Quinolones
Reduce absorption of both iron and antibiotics. Take iron 2 hours before or 4-6 hours after.
Storage
Store below 30°C in a dry place, protected from light. Keep out of reach of children.
Overdose
Symptoms include severe gastrointestinal upset, metabolic acidosis, cardiovascular collapse. Seek immediate medical attention. Treatment involves gastric lavage, chelation therapy (e.g., deferoxamine) if severe.
Pregnancy & Lactation
Considered safe and often recommended for iron and vitamin deficiencies during pregnancy and lactation. Consult a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months from manufacturing date.
Availability
Pharmacies, drugstores, supermarkets
Approval Status
Approved by regulatory authorities
Patent Status
Generic (Patent expired)
WHO Essential Medicine
YesClinical Trials
Extensive clinical data supports the efficacy of iron, folic acid, and B12 combinations in treating and preventing respective deficiencies.
Lab Monitoring
- Hemoglobin and hematocrit levels
- Serum ferritin
- Transferrin saturation
Doctor Notes
- Advise patients on dietary iron sources and Vitamin C intake.
- Educate on potential dark stools, which are harmless.
Patient Guidelines
- Take as directed by your physician.
- Do not exceed the recommended dose.
- Store in a cool, dry place away from children.
Missed Dose Advice
Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double the dose.
Driving Precautions
No known adverse effects on driving or operating machinery.
Lifestyle Advice
- Maintain a balanced diet rich in iron (e.g., red meat, leafy greens).
- Include Vitamin C-rich foods to enhance iron absorption.
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