Fertil
Generic Name
Clomiphene Citrate
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fertil 50 mg tablet | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Fertil (Clomiphene Citrate) is a non-steroidal fertility medicine used to induce ovulation in women who are unable to conceive due to ovulatory dysfunction.
Uses & Indications
Dosage
Adults
50 mg once daily for 5 days, starting on or about the 5th day of the menstrual cycle. May be increased to 100 mg if no ovulation occurs.
Elderly
Not applicable for this indication.
Renal_impairment
Use with caution; specific dosage adjustments not well-established.
How to Take
Take orally with or without food, exactly as directed by the doctor. It is typically taken for 5 days starting early in the menstrual cycle.
Mechanism of Action
Clomiphene blocks estrogen receptors in the hypothalamus, leading to an increased release of gonadotropins (FSH and LH) from the pituitary gland. These gonadotropins stimulate ovarian follicular growth and ovulation.
Pharmacokinetics
Onset
Ovulation typically occurs 5-10 days after the last dose.
Excretion
Primarily excreted via feces, with some renal excretion.
Half life
Approximately 5-7 days.
Absorption
Rapidly absorbed after oral administration.
Metabolism
Metabolized in the liver.
Side Effects
Contraindications
- •Pregnancy
- •Undiagnosed abnormal uterine bleeding
- •Ovarian cyst (other than polycystic ovary syndrome)
- •Liver disease or history of liver dysfunction
- •Thrombophlebitis
- •Tumor of the pituitary gland
Drug Interactions
Danazol
May increase ovarian response to clomiphene.
Gonadotropins
May increase the risk of Ovarian Hyperstimulation Syndrome (OHSS).
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, hot flushes, pelvic pain, visual blurring. Management is symptomatic and supportive.
Pregnancy & Lactation
Contraindicated in pregnancy. Not recommended during lactation as it may decrease milk production.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA and FDA
Patent Status
Generic available, original patent expired
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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