Flindof
Generic Name
Flinodofen
Manufacturer
Hypothetical Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| flindof 400 mg tablet | ৳ 10.00 | ৳ 100.00 |
Description
Overview of the medicine
Flindof 400 mg Tablet is a non-steroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and fever. It helps alleviate pain caused by various conditions such as arthritis, muscle aches, and menstrual pain.
Uses & Indications
Dosage
Adults
400 mg every 6-8 hours, not exceeding 1200 mg/day. Take with food or milk.
Elderly
Lower doses may be required, closely monitor for adverse effects. Consult a physician.
Renal_impairment
Dose adjustment necessary, consult a physician based on creatinine clearance.
How to Take
Take Flindof 400 mg Tablet orally with food or milk to minimize gastrointestinal upset. Swallow the whole tablet with a glass of water; do not chew or crush it.
Mechanism of Action
It works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, which leads to a reduction in the production of prostaglandins, chemicals that play a role in causing pain, inflammation, and fever.
Pharmacokinetics
Onset
Within 30-60 minutes
Excretion
Mainly renal, as metabolites and unchanged drug
Half life
Approximately 2-4 hours
Absorption
Oral administration results in rapid and complete absorption. Peak plasma concentrations are typically reached within 1-2 hours.
Metabolism
Primarily hepatic, via oxidation and conjugation
Side Effects
Contraindications
- •Hypersensitivity to Flindof or other NSAIDs
- •Active peptic ulcer or gastrointestinal bleeding
- •Severe renal or hepatic impairment
- •Third trimester of pregnancy
- •History of asthma, urticaria, or allergic reactions to aspirin or other NSAIDs
Drug Interactions
Lithium
May increase lithium plasma levels and toxicity.
Diuretics
May reduce diuretic and antihypertensive effects.
Methotrexate
May increase methotrexate toxicity.
ACE inhibitors and ARBs
May reduce antihypertensive effect and increase risk of renal impairment.
Warfarin and other anticoagulants
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children. Do not freeze.
Overdose
Symptoms of overdose may include abdominal pain, nausea, vomiting, drowsiness, and headache. In severe cases, gastrointestinal bleeding, acute renal failure, and respiratory depression may occur. Seek immediate medical attention. Management is symptomatic and supportive.
Pregnancy & Lactation
Consult a physician before use during pregnancy (especially in the third trimester) and lactation, as NSAIDs can pose risks to the fetus and infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA/FDA for general use (hypothetical)
Patent Status
Off-patent (hypothetical)
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Global Brand Names
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