Flonor
Generic Name
Fluticasone Propionate
Manufacturer
Reputable Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| flonor 04 mg capsule | ৳ 10.03 | N/A |
Description
Overview of the medicine
Flonor is a corticosteroid nasal spray containing Fluticasone Propionate. It is used to relieve symptoms of seasonal and perennial allergic rhinitis, such as sneezing, runny nose, itching, and congestion.
Uses & Indications
Dosage
Adults
Two sprays in each nostril once daily. May be reduced to one spray per nostril once daily for maintenance.
Elderly
Same as adult dosage. No specific dose adjustment needed.
Renal_impairment
No dose adjustment required.
How to Take
Shake the bottle gently before use. Clear your nasal passages. Insert the nozzle into one nostril and spray while closing the other nostril. Breathe in gently through your nose. Repeat for the other nostril. Clean the nozzle after use.
Mechanism of Action
Fluticasone Propionate is a synthetic trifluorinated corticosteroid that possesses potent anti-inflammatory activity. It works by reducing the inflammation in the nasal passages, thereby alleviating allergic symptoms.
Pharmacokinetics
Onset
Onset of action typically within 12 hours, with full effect achieved within several days.
Excretion
Primarily excreted in feces as metabolites.
Half life
Systemic half-life is approximately 7.8 hours.
Absorption
Low systemic absorption following nasal administration, approximately 1-2% bioavailability.
Metabolism
Extensive first-pass metabolism in the liver by CYP3A4.
Side Effects
Contraindications
- •Hypersensitivity to fluticasone propionate or any component of the formulation
- •Untreated localized infection involving the nasal mucosa
Drug Interactions
Ritonavir
Concurrent use may significantly increase systemic fluticasone exposure, leading to Cushing's syndrome and adrenal suppression.
Ketoconazole
May increase fluticasone levels, though less pronounced than ritonavir.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose is unlikely due to low systemic absorption. Chronic high doses may lead to systemic corticosteroid effects. Treatment is symptomatic and supportive.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit justifies potential risk to the fetus. Caution advised during lactation; consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years (unopened), 2 months after first opening
Availability
Available in pharmacies nationwide
Approval Status
Approved by regulatory authorities worldwide, including DGDA
Patent Status
Generic versions available, original patent expired
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Global Brand Names
International brand names for this medicine
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