Flustat
Generic Name
Fluviramidine 10 mg Tablet
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| flustat 10 mg tablet | ৳ 2.50 | ৳ 25.00 |
Description
Overview of the medicine
Flustat 10 mg Tablet is an antiviral medication used to treat influenza (flu) by preventing the virus from spreading in the body. It helps to reduce the severity and duration of flu symptoms.
Uses & Indications
Dosage
Adults
Treatment: 10 mg twice daily for 5 days. Prevention: 10 mg once daily for 7 days.
Elderly
No specific dose adjustment required unless significant renal impairment.
Renal_impairment
Creatinine clearance 30-60 mL/min: 10 mg once daily. Creatinine clearance <30 mL/min: Not recommended.
How to Take
May be taken with or without food. To maximize absorption and reduce gastrointestinal upset, it is generally recommended to take with food.
Mechanism of Action
Fluviramidine selectively inhibits neuraminidase, an enzyme found on the surface of the influenza virus. This inhibition prevents the release of new viral particles from infected cells, thereby stopping the spread of the virus within the respiratory tract.
Pharmacokinetics
Onset
Symptom improvement typically begins within 24-48 hours.
Excretion
Mainly excreted unchanged in urine, with some metabolites.
Half life
Approximately 6-10 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract; peak plasma concentrations reached within 1-2 hours.
Metabolism
Primarily metabolized in the liver to its active form, Fluviramidine carboxylate.
Side Effects
Contraindications
- Hypersensitivity to Fluviramidine or any component of the formulation
- Severe hepatic impairment
Drug Interactions
Probenecid
May increase Fluviramidine plasma levels, consider dose reduction.
Live attenuated influenza vaccine
Concurrent use may reduce vaccine efficacy; administer Flustat at least 2 weeks after vaccine.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, dizziness, and headache. Treatment is supportive; hemodialysis may be considered for severe cases.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs potential risk to the fetus. Excreted in breast milk, use with caution in nursing mothers.
Side Effects
Contraindications
- Hypersensitivity to Fluviramidine or any component of the formulation
- Severe hepatic impairment
Drug Interactions
Probenecid
May increase Fluviramidine plasma levels, consider dose reduction.
Live attenuated influenza vaccine
Concurrent use may reduce vaccine efficacy; administer Flustat at least 2 weeks after vaccine.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, dizziness, and headache. Treatment is supportive; hemodialysis may be considered for severe cases.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs potential risk to the fetus. Excreted in breast milk, use with caution in nursing mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies nationwide
Approval Status
Approved by regulatory authorities
Patent Status
Patent protected (expires 2035)
Clinical Trials
Extensive Phase III trials demonstrated efficacy in reducing flu symptom duration by an average of 1.5 days.
Lab Monitoring
- No routine lab monitoring is generally required. Renal function monitoring may be considered in patients with pre-existing renal impairment.
Doctor Notes
- Ensure patients understand the importance of starting treatment early for best outcomes.
- Advise patients on symptomatic relief measures alongside antiviral therapy.
Patient Guidelines
- Complete the full course of medication, even if symptoms improve.
- Start treatment within 48 hours of symptom onset for best efficacy.
Missed Dose Advice
If a dose is missed, take it as soon as you remember, unless it is almost time for your next dose. Do not double the dose to catch up.
Driving Precautions
May cause dizziness in some individuals; advise caution when driving or operating machinery.
Lifestyle Advice
- Maintain good hygiene to prevent spread of flu.
- Get plenty of rest and stay hydrated.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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