Fondy
Generic Name
Fexofenadine Hydrochloride
Manufacturer
Hypothetical Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fondy 120 mg tablet | ৳ 8.00 | ৳ 80.00 |
Description
Overview of the medicine
Fexofenadine is a non-sedating antihistamine used to relieve symptoms of seasonal allergic rhinitis (hay fever), including sneezing, runny nose, itchy nose/palate/throat, and itchy watery eyes. It is also used to treat symptoms of chronic idiopathic urticaria (hives), such as itching and rash.
Uses & Indications
Dosage
Adults
For seasonal allergic rhinitis: 180 mg orally once daily. For chronic idiopathic urticaria: 120 mg orally once daily.
Elderly
No specific dosage adjustment is generally recommended for elderly patients with normal renal function.
Renal_impairment
For patients with impaired renal function (creatinine clearance < 80 mL/min), a starting dose of 60 mg once daily is recommended. For severe renal impairment or dialysis, consult a physician.
How to Take
Take orally with water, with or without food. Avoid taking with fruit juice.
Mechanism of Action
Fexofenadine is a selective peripheral H1-receptor antagonist. It blocks the action of histamine, a natural substance in the body that causes allergic symptoms. By blocking histamine, it helps to relieve symptoms like sneezing, itching, and runny nose without causing significant drowsiness.
Pharmacokinetics
Onset
Within 1 hour (for allergic rhinitis symptoms)
Excretion
Approximately 80% excreted in feces and 11% in urine, largely as unchanged drug.
Half life
Approximately 14 hours
Absorption
Rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations reached approximately 1-3 hours after oral administration.
Metabolism
Minimally metabolized; less than 5% of a dose is metabolized in the liver.
Side Effects
Contraindications
- •Hypersensitivity to fexofenadine or any components of the formulation.
Drug Interactions
Erythromycin
May increase fexofenadine plasma concentrations.
Ketoconazole
May increase fexofenadine plasma concentrations.
Aluminum and Magnesium-containing antacids
Decrease fexofenadine absorption; separate administration by at least 2 hours.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Overdose symptoms may include dizziness, drowsiness, and dry mouth. Management is symptomatic and supportive, including gastric lavage and activated charcoal if appropriate.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs risk. Excreted in breast milk in animal studies; caution advised in breastfeeding mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, hospitals
Approval Status
Approved by regulatory authorities worldwide
Patent Status
Generic available, patents expired
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