Frenia
Generic Name
Risperidone
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| frenia 2 mg tablet | ৳ 5.00 | ৳ 50.00 |
Description
Overview of the medicine
Frenia 2 mg tablet is an atypical antipsychotic medication used to treat schizophrenia, bipolar mania, and irritability associated with autistic disorder. It helps to restore the balance of certain natural substances in the brain.
Uses & Indications
Dosage
Adults
Typical starting dose 0.5-2 mg/day, target 2-8 mg/day, divided into one or two doses.
Elderly
Lower starting doses (e.g., 0.25 mg BID), gradual titration.
Renal_impairment
Lower starting doses (e.g., 0.25 mg BID), careful titration.
How to Take
Take orally with or without food, usually once or twice a day as directed by your doctor.
Mechanism of Action
Risperidone acts by blocking dopamine D2 and serotonin 5-HT2A receptors in the brain, which helps to alleviate symptoms of schizophrenia and other mental conditions.
Pharmacokinetics
Onset
Rapid (within hours for some effects, full antipsychotic effect takes days/weeks).
Excretion
Mainly renal.
Half life
Risperidone: ~3 hours; Active metabolite (9-hydroxyrisperidone): ~20-24 hours.
Absorption
Well absorbed orally.
Metabolism
Hepatic (CYP2D6, CYP3A4).
Side Effects
Contraindications
- Hypersensitivity to Risperidone or any component of the formulation
- Severe central nervous system (CNS) depression
Drug Interactions
Antihypertensive agents
May potentiate hypotensive effects.
Carbamazepine (CYP3A4 inducer)
May decrease plasma concentrations of risperidone.
CNS depressants (e.g., alcohol, benzodiazepines)
May potentiate sedative effects.
CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
May increase plasma concentrations of risperidone.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, tachycardia, hypotension, and extrapyramidal symptoms. Management is supportive, including maintaining an open airway, ensuring adequate oxygenation and ventilation, and managing symptoms.
Pregnancy & Lactation
Pregnancy Category C (Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks). Use with caution during lactation; consult your doctor.
Side Effects
Contraindications
- Hypersensitivity to Risperidone or any component of the formulation
- Severe central nervous system (CNS) depression
Drug Interactions
Antihypertensive agents
May potentiate hypotensive effects.
Carbamazepine (CYP3A4 inducer)
May decrease plasma concentrations of risperidone.
CNS depressants (e.g., alcohol, benzodiazepines)
May potentiate sedative effects.
CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
May increase plasma concentrations of risperidone.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include drowsiness, tachycardia, hypotension, and extrapyramidal symptoms. Management is supportive, including maintaining an open airway, ensuring adequate oxygenation and ventilation, and managing symptoms.
Pregnancy & Lactation
Pregnancy Category C (Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks). Use with caution during lactation; consult your doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved
Patent Status
Off-patent (Generic available)
WHO Essential Medicine
YesClinical Trials
Risperidone has been extensively studied in numerous clinical trials demonstrating its efficacy and safety across its approved indications.
Lab Monitoring
- Blood glucose levels
- Lipid profile
- Prolactin levels
- Weight/BMI
- Complete Blood Count (CBC) if clinically indicated
Doctor Notes
- Monitor patients for extrapyramidal symptoms (EPS), metabolic changes (weight, glucose, lipids), and prolactin levels regularly.
- Consider lower doses in elderly patients and those with renal/hepatic impairment.
- Educate patients about the black box warning regarding increased mortality in elderly patients with dementia-related psychosis.
Patient Guidelines
- Do not stop taking this medicine abruptly without consulting your doctor.
- Avoid alcohol while on this medication.
- Report any unusual or severe side effects to your doctor immediately.
Missed Dose Advice
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not double dose.
Driving Precautions
This medicine may cause drowsiness, dizziness, or blurred vision. Do not drive or operate heavy machinery until you know how it affects you.
Lifestyle Advice
- Maintain a healthy diet and regular exercise to manage weight.
- Avoid illicit drugs.
- Stay hydrated.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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