Fungitac
Generic Name
Fluconazole
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| fungitac 2 cream | ৳ 200.00 | N/A |
Description
Overview of the medicine
Fungitac (Fluconazole) is an antifungal medication used to treat various fungal infections, including candidiasis, cryptococcal meningitis, and dermatophytosis.
Uses & Indications
Dosage
Adults
For vaginal candidiasis: 150 mg single oral dose. For other infections: 50-400 mg once daily, depending on the type and severity of infection.
Elderly
No specific dose adjustment for elderly unless renal impairment is present; refer to renal impairment guidelines.
Renal_impairment
Dose reduction required based on creatinine clearance; e.g., CrCl 21-50 mL/min, 50% of recommended dose.
How to Take
Can be taken orally with or without food.
Mechanism of Action
Inhibits fungal cytochrome P450-dependent 14-alpha-demethylase, which is essential for ergosterol synthesis in fungal cell membranes, leading to cell death.
Pharmacokinetics
Onset
Variable, depending on infection type and location.
Excretion
Primarily renal excretion (approximately 80% as unchanged drug).
Half life
Approximately 20-50 hours.
Absorption
Well absorbed orally. Bioavailability typically >90%.
Metabolism
Minimally metabolized; 11% is metabolized.
Side Effects
Contraindications
- •Hypersensitivity to fluconazole or any excipients
- •Co-administration with terfenadine or cisapride (due to risk of QT prolongation)
Drug Interactions
Warfarin
May increase prothrombin time; monitor INR.
Phenytoin
Increases phenytoin levels; monitor levels.
Rifampicin
Decreases fluconazole concentration.
Oral Hypoglycemics
May increase blood glucose lowering effect.
Storage
Store below 30°C, protected from light and moisture. Keep out of reach of children.
Overdose
Symptoms may include hallucinations and paranoid behavior. Treatment is symptomatic and supportive; hemodialysis can reduce plasma levels.
Pregnancy & Lactation
Pregnancy Category D (single dose for vaginal candidiasis is C). Avoid in pregnancy unless potential benefit outweighs risk. Excreted in breast milk; use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years
Availability
Pharmacies, Hospitals
Approval Status
Approved by major regulatory bodies
Patent Status
Generic available
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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