G-Hyoscine
Generic Name
g-hyoscine-10-mg-tablet
Manufacturer
Meditech Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| g hyoscine 10 mg tablet | ৳ 3.50 | ৳ 35.00 |
Description
Overview of the medicine
G-Hyoscine 10 mg Tablet contains Hyoscine Butylbromide, an antispasmodic agent used to relieve cramps or spasms of the stomach, intestines, and bladder.
Uses & Indications
Dosage
Adults
Oral: 10-20 mg three to five times daily. Max 100 mg/day.
Elderly
Similar to adult dose, but caution is advised in elderly patients with existing conditions like prostatic hypertrophy or narrow-angle glaucoma.
Renal_impairment
Use with caution; dose adjustment may be necessary in severe renal impairment. Consult a physician.
How to Take
Swallow the tablet whole with water. Can be taken with or without food.
Mechanism of Action
Hyoscine Butylbromide acts by blocking the muscarinic acetylcholine receptors in the smooth muscles of the gastrointestinal tract, urinary tract, and biliary tract, leading to relaxation and relief of spasms.
Pharmacokinetics
Onset
Oral: 15-30 minutes; IV/IM: rapid.
Excretion
Mainly via urine and feces in unchanged and metabolized forms.
Half life
Short terminal elimination half-life, typically a few hours (e.g., ~4.5 hours).
Absorption
Poorly absorbed from the gastrointestinal tract (low oral bioavailability <10%).
Metabolism
Partially metabolized via ester hydrolysis. Metabolized predominantly outside the liver.
Side Effects
Contraindications
- •Hypersensitivity to Hyoscine Butylbromide or any component of the formulation
- •Untreated narrow-angle glaucoma
- •Prostatic hypertrophy with urinary retention
- •Mechanical stenosis of the gastrointestinal tract
- •Paralytic or obstructive ileus
- •Tachycardia
- •Myasthenia gravis
- •Megacolon
Drug Interactions
Beta-adrenergics
Increased heart rate.
Dopamine antagonists (e.g., metoclopramide)
Reduced prokinetic effect of dopamine antagonists.
Anticholinergics (e.g., tricyclic antidepressants, antihistamines)
Potentiation of anticholinergic effects.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include dry mouth, blurred vision, tachycardia, urinary retention, and skin redness. Management is symptomatic and supportive; physostigmine may be considered in severe cases.
Pregnancy & Lactation
Pregnancy Category C. Use only if clearly needed and the potential benefits outweigh the potential risks. Consult your doctor before use during pregnancy or lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from manufacturing date
Availability
Available in pharmacies and hospitals
Approval Status
Approved by regulatory authorities (e.g., DGDA)
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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