Genmax
Generic Name
Gentamicin 0.3% Eye Ointment
Manufacturer
XYZ Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| genmax 03 eye ointment | ৳ 9.03 | N/A |
Description
Overview of the medicine
Genmax-03 Eye Ointment contains Gentamicin, an aminoglycoside antibiotic, used to treat bacterial infections of the eye such as conjunctivitis, keratitis, and blepharitis.
Uses & Indications
Dosage
Adults
Apply a small ribbon (approx. 1 cm) into the conjunctival sac 2-3 times daily, or as directed by a physician.
Elderly
No specific dosage adjustment required; use as per adult dosage.
Renal_impairment
No dosage adjustment needed for topical ocular use due to minimal systemic absorption.
How to Take
Wash hands before and after application. Pull down the lower eyelid to create a pocket. Apply a small amount of ointment into the pocket. Close the eye gently for 1-2 minutes. Avoid touching the tube tip to the eye or any surface.
Mechanism of Action
Gentamicin binds to the 30S ribosomal subunit of susceptible bacteria, inhibiting protein synthesis and leading to bacterial cell death.
Pharmacokinetics
Onset
Within hours of application.
Excretion
Primarily excreted unchanged if absorbed systemically, though ocular absorption is minimal.
Half life
Not significant systemically; locally, sustained release from ointment.
Absorption
Minimal systemic absorption following ocular administration.
Metabolism
Not significantly metabolized.
Side Effects
Contraindications
- Hypersensitivity to gentamicin or any component of the formulation
- Viral or fungal eye infections
Drug Interactions
Systemic Drugs
No significant systemic drug interactions expected due to minimal ocular absorption. However, avoid concomitant use with other topical ophthalmic preparations unless advised by a physician, to prevent dilution or altered absorption.
Storage
Store below 30°C. Do not freeze. Keep away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose with topical ophthalmic gentamicin is unlikely to cause systemic toxicity due to minimal absorption. If accidental oral ingestion occurs, seek medical attention. Symptomatic and supportive treatment.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the potential benefit outweighs the potential risk to the fetus. Caution should be exercised when administered to a nursing mother. Consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to gentamicin or any component of the formulation
- Viral or fungal eye infections
Drug Interactions
Systemic Drugs
No significant systemic drug interactions expected due to minimal ocular absorption. However, avoid concomitant use with other topical ophthalmic preparations unless advised by a physician, to prevent dilution or altered absorption.
Storage
Store below 30°C. Do not freeze. Keep away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose with topical ophthalmic gentamicin is unlikely to cause systemic toxicity due to minimal absorption. If accidental oral ingestion occurs, seek medical attention. Symptomatic and supportive treatment.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the potential benefit outweighs the potential risk to the fetus. Caution should be exercised when administered to a nursing mother. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date (unopened). Discard 4 weeks after opening the tube.
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by health authorities
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Gentamicin ophthalmic formulations have been extensively studied and are widely used for the treatment of various ocular bacterial infections, demonstrating proven efficacy.
Lab Monitoring
- Not typically required for topical ocular gentamicin.
- Monitor for signs of infection resolution.
Doctor Notes
- Advise patients on proper application technique to maximize efficacy and minimize contamination.
- Emphasize completion of the full course of treatment to prevent recurrence and resistance.
- Counsel patients on potential temporary blurred vision post-application and the importance of avoiding contact lenses during treatment.
Patient Guidelines
- Complete the full course of treatment even if symptoms improve.
- Do not wear contact lenses during treatment.
- Avoid sharing eye drops/ointments to prevent spread of infection.
- If irritation persists or worsens, consult your doctor.
- Avoid touching the tip of the ointment tube to the eye or other surfaces to prevent contamination.
Missed Dose Advice
Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not apply a double dose.
Driving Precautions
May cause temporary blurred vision immediately after application. If affected, avoid driving or operating machinery until vision clears.
Lifestyle Advice
- Maintain good eye hygiene.
- Avoid rubbing eyes.
- Protect eyes from irritants like dust and smoke.
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Global Brand Names
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